WIF1 and RPL37

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		WIF1	RPL37
Description		WNT inhibitory factor 1	ribosomal protein L37
Image
GO Annotations	Cellular Component	Extracellular Region Cell Surface	Cytosol Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Synapse
	Molecular Function	Signaling Receptor Binding Protein Binding Wnt-protein Binding	RNA Binding Structural Constituent Of Ribosome RRNA Binding Metal Ion Binding MDM2/MDM4 Family Protein Binding Ubiquitin Ligase Inhibitor Activity
	Biological Process	Signal Transduction Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Fat Cell Differentiation Anatomical Structure Development	Cytoplasmic Translation Translation Positive Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity
Pathways		TCF dependent signaling in response to WNT Negative regulation of TCF-dependent signaling by WNT ligand antagonists	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			(S)-3-phenyllactic acid PUROMYCIN AMINONUCLEOSIDE-5'-MONOPHOSPHATE Virginiamycin S1 Anisomycin Puromycin
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal fissure volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA1 volume (corrected for total hippocampal volume) ( 30279459) Hippocampal subfield CA3 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal volume ( 22504421) Macular thickness ( 30535121) Post bronchodilator FEV1/FVC ratio ( 26634245) Subiculum volume ( 30279459) Total hippocampal volume ( 30279459)
Interacting Genes		9 interacting genes: AURKA CRADD CYSRT1 FGFR4 ICOS KRTAP10-3 KRTAP10-8 RB1CC1 RPL37	6 interacting genes: APP POLR1B SQSTM1 SRPK2 TCF3 WIF1
Entrez ID		11197	6167
HPRD ID		05541	16047
Ensembl ID		ENSG00000156076	ENSG00000145592
Uniprot IDs		Q9Y5W5	P61927
PDB IDs		2D3J 2YGN 2YGO 2YGP 2YGQ	4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP
Enriched GO Terms of Interacting Partners?
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