ACE2 and MAST1

Data Source:
BioGRID (pull down)

		ACE2	MAST1
Description		angiotensin converting enzyme 2	microtubule associated serine/threonine kinase 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Cilium Cell Surface Integral Component Of Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Brush Border Membrane Membrane Raft Extracellular Exosome	Cytoplasm Cytoskeleton Plasma Membrane Axon Dendrite Neuron Projection Neuronal Cell Body
	Molecular Function	Virus Receptor Activity Endopeptidase Activity Carboxypeptidase Activity Metallocarboxypeptidase Activity Protein Binding Metallopeptidase Activity Peptidyl-dipeptidase Activity Zinc Ion Binding Identical Protein Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Cytokine Production Angiotensin Maturation Angiotensin-mediated Drinking Behavior Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Tryptophan Transport Regulation Of Vasoconstriction Regulation Of Transmembrane Transporter Activity Regulation Of Cell Population Proliferation Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Regulation Of Inflammatory Response Positive Regulation Of Amino Acid Transport Positive Regulation Of Cardiac Muscle Contraction Blood Vessel Diameter Maintenance Positive Regulation Of Gap Junction Assembly Regulation Of Cardiac Conduction Positive Regulation Of L-proline Import Across Plasma Membrane Negative Regulation Of Signaling Receptor Activity Positive Regulation Of Reactive Oxygen Species Metabolic Process	Protein Phosphorylation Cytoskeleton Organization Brain Development Peptidyl-serine Phosphorylation Intracellular Signal Transduction
Pathways		Metabolism of Angiotensinogen to Angiotensins Attachment and Entry Potential therapeutics for SARS Attachment and Entry Attachment and Entry
Drugs		Chloroquine Hydroxychloroquine SPP1148 N-(2-Aminoethyl)-1-aziridineethanamine	Fostamatinib
Diseases
GWAS			High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 29403010 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494 27863252) Red blood cell count ( 29403010) Reticulocyte fraction of red cells ( 32888494)
Interacting Genes		25 interacting genes: AGT CALM1 CDSN DEFA5 DLEU2 GHRL MAST1 MAST2 NTS PARD3 PDZK1 PTPN3 SCRIB SHANK1 SHANK2 SHANK3 SHROOM2 SLC6A19 SLC9A3R1 SLC9A3R2 SNX17 SNX27 TAMALIN TMPRSS11A TMPRSS11D	41 interacting genes: A2M ACE2 AP1M2 APOE APP BLMH CDK5 CYP2C8 CYP2C9 DNAJB1 ECSIT EGFR ELAVL3 EXOC6 EXOSC1 FBXL12 FBXW4 GCDH HSP90AB1 IFIT3 IFIT5 LONP1 LOXL4 NOS3 OGA PAXIP1 PRAM1 PRDX2 PSEN2 PTEN RAB3A RAB3D RAD23A RNF32 RNLS RPP30 RPS6KA1 SNTA1 SNTB2 STAMBPL1 STUB1
Entrez ID		59272	22983
HPRD ID		02274	17469
Ensembl ID		ENSG00000130234	ENSG00000105613
Uniprot IDs		Q9BYF1	Q9Y2H9
PDB IDs		1R42 1R4L 1XJP 2AJF 3D0G 3D0H 3D0I 3KBH 3SCI 3SCJ 3SCK 3SCL 6ACG 6ACJ 6ACK 6CS2 6LZG 6M0J 6M17 6M18 6M1D 6VW1 7A91 7A92 7A94 7A95 7A96 7A97 7A98 7BH9 7CT5 7DF4 7DMU 7JVO 7KJ2 7KJ3 7KJ4 7KMB 7KMS 7KMZ 7KNB 7KNE 7KNH 7KNI 7L0N 7L7F	2M9X 3PS4
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?