RAPSN and CHRNB1

Number of citations of the paper that reports this interaction (PubMedID 16280586)
27

Data Source:
HPRD (in vivo)

		RAPSN	CHRNB1
Description		receptor associated protein of the synapse	cholinergic receptor nicotinic beta 1 subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Centrosome Cytosol Plasma Membrane Neuromuscular Junction Postsynaptic Specialization Membrane	Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Neuromuscular Junction Neuron Projection Synapse Integral Component Of Postsynaptic Specialization Membrane
	Molecular Function	Acetylcholine Receptor Binding Ionotropic Glutamate Receptor Binding Protein-membrane Adaptor Activity Metal Ion Binding	Protein Binding Channel Activity Ligand-gated Ion Channel Activity Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity Acetylcholine Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Neuromuscular Synaptic Transmission Regulation Of Postsynaptic Membrane Organization Establishment Of Protein Localization To Postsynaptic Membrane	Postsynaptic Membrane Organization Skeletal Muscle Contraction Cation Transport Muscle Contraction Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Ion Transmembrane Transport Behavioral Response To Nicotine Regulation Of Membrane Potential Nervous System Process Muscle Cell Development Excitatory Postsynaptic Potential
Pathways
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258 30679032) Alcohol use disorder (total score) ( 30336701) Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Central corneal thickness ( 32528159) Diastolic blood pressure ( 28739976 27618452) Eosinophil counts ( 32888494) Eosinophil percentage of white cells ( 32888494) Fruit consumption ( 32066663) General factor of neuroticism ( 30867560) Glaucoma (primary open-angle) ( 33627673) Global electrical heterogeneity phenotypes ( 29622589) Height ( 28552196) Intraocular pressure ( 29617998 25173106 29235454) Lacunar stroke ( 33773637) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mood instability ( 31168069) Neuroticism ( 29255261) Red cell distribution width ( 32888494) Refractive error ( 32231278) Sleep duration (short sleep) ( 30846698) Systolic blood pressure ( 28739976 27618452) Type 2 diabetes or prostate cancer (pleiotropy) ( 33290408) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) White blood cell count ( 29403010)	Brain morphology (MOSTest) ( 32665545) Emotional recognition ( 31596458) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		8 interacting genes: CHRNB1 DAG1 GRB2 KHDRBS1 KLHL8 MUSK TRIM54 UBE2Z	3 interacting genes: ASB6 COPS6 RAPSN
Entrez ID		5913	1140
HPRD ID		03353	01156
Ensembl ID		ENSG00000165917	ENSG00000170175
Uniprot IDs		A0A0S2Z4A2 A0A0S2Z4A6 A0A0S2Z4F8 A0A0S2Z4M9 Q13702	P11230
PDB IDs
Enriched GO Terms of Interacting Partners?
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