Description |
Raf-1 proto-oncogene, serine/threonine kinase |
BCL6 transcription repressor |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Asthma ( 32296059)
- Body shape index ( 34021172)
- Cardiac hypertrophy ( 21348951)
- Carotid intima media thickness x smoking interaction ( 32117412)
- Cholesterol, total ( 24097068 20686565)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- HDL cholesterol levels ( 32203549)
- Hip index ( 34021172)
- Total cholesterol levels ( 28334899)
- Waist circumference adjusted for body mass index ( 34021172)
- Waist-hip index ( 34021172)
- Waist-to-hip ratio adjusted for BMI ( 34021172 26426971)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
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Interacting Genes |
160 interacting genes:
ABCB5
ADCY6
AGTR1
AKT1
AR
ARNT
ARRB2
BAD
BAG1
BCL2
BCL2L1
BCL6
BECN1
BIRC2
BIRC3
BRAF
CASZ1
CBLC
CCND2
CCT3
CD44
CDC25A
CDC37
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CFLAR
CNKSR1
COPS3
COPS7A
CPS1
DCAF8
DMPK
EFEMP1
EGFR
EPHA2
ERBB2
ERBIN
FGFR4
FYCO1
FYN
GLIS2
GNB2
GNG4
GRB10
GRM1
HERC1
HGF
HRAS
HSP90AA1
HSPA4
HSPA8
IL2RB
INSR
INTS10
ITCH
JAK1
JAK2
KEAP1
KRAS
KRT18
KRT8
KSR1
KSR2
LATS2
LCK
LOX
LRPAP1
MAP2K1
MAP2K2
MAP2K3
MAP2K5
MAP2K6
MAP3K1
MAP3K5
MAPK1
MAPK3
MAPK7
MAPK8
MAPK8IP3
MBP
MET
MRAS
MRC2
MYBPC1
MYC
NEDD4
NF1
NF2
NPLOC4
NR3C1
NRAS
NUDT14
OIP5
PACSIN3
PAK1
PAK2
PAK3
PBK
PDGFRA
PDGFRB
PDLIM2
PEBP1
PEBP4
PEX5L
PHB
PHKA2
PIN1
PKM
PPP1CC
PPP2CB
PRKAA1
PRKACA
PRKAR1A
PRKCA
PRKCD
PRKCE
PRKCZ
PRKG1
PRPF6
PURA
RANBP9
RAP1A
RAP2A
RASD2
RASSF1
RB1
RBBP8
RBL2
RFXANK
RHEB
RRAS
RRAS2
RSU1
SHOC2
SPRY2
SPRY4
SRC
STK26
STK3
STUB1
TBXA2R
TEAD2
TERT
TIMM50
TMEM70
TSC22D3
UBE2D2
VAV1
VDAC1
XIAP
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
YY1
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90 interacting genes:
ANKRD53
ARHGEF9
ARRDC3
ATP23
BCL11A
BCL6B
BCOR
BLZF1
C4orf45
C7orf31
C9orf24
CABP4
CDK19
CDK8
CFAP161
CFAP97D1
CHD3
CNOT2
CRBN
CREBBP
CTNNB1
CUTC
DVL2
DVL3
ENO1
EP300
FBXO11
GATA1
GLRX3
GOLGA2
HDAC1
HDAC4
HDAC5
HDAC7
HDAC9
IHO1
IRF4
JUN
JUNB
JUND
KIFC3
KLHL12
KLHL20
KRTAP13-1
KRTAP13-2
KRTAP19-1
LIMS3
LIMS4
MAPK1
MDFI
MED17
MED6
MTA3
MTUS2
NCOR1
NCOR2
PBX4
PELI1
PFDN5
PIN1
PML
POF1B
PPARD
PPTC7
PRKD3
PSMB4
RAF1
REL
RUNX1T1
SIAH1
SIN3A
SP1
SPI1
SSX2IP
TEKT4
TFIP11
TLE5
TP53
TP53BP1
TRAF1
TRAF2
TRIB3
TWIST1
WDR83
WNK4
ZBTB16
ZBTB17
ZBTB7A
ZBTB7B
ZNHIT1
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Entrez ID |
5894 |
604 |
HPRD ID |
01265 |
00180 |
Ensembl ID |
ENSG00000132155
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ENSG00000113916
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Uniprot IDs |
A0A0S2Z4L5
L7RRS6
P04049
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B5B0A5
P41182
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PDB IDs |
1C1Y
1FAQ
1FAR
1GUA
1RFA
3CU8
3IQJ
3IQU
3IQV
3KUC
3KUD
3NKX
3O8I
3OMV
4FJ3
4G0N
4G3X
4IEA
4IHL
6NTC
6NTD
6PTS
6PTW
6VJJ
6XGU
6XGV
6XHA
6XHB
6XI7
7JHP
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1R28
1R29
1R2B
2EN2
2EOS
2LCE
2YRM
3BIM
3E4U
3LBZ
4CP3
4U2M
5H7G
5H7H
5MW2
5MW6
5MWD
5N1X
5N1Z
5N20
5N21
5X4M
5X4N
5X4O
5X4P
5X4Q
5X9O
5X9P
6C3L
6C3N
6CQ1
6EW6
6EW7
6EW8
6TOF
6TOG
6TOH
6TOI
6TOJ
6TOK
6TOL
6TOM
6TON
6TOO
6XMX
6XWF
6XXS
6XYX
6XZZ
6Y17
6ZBU
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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