RAB13 and VPS45

		RAB13	VPS45
Description		RAB13, member RAS oncogene family	vacuolar protein sorting 45 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Bicellular Tight Junction Synaptic Vesicle Lateral Plasma Membrane Lamellipodium Cell Junction Endocytic Vesicle Trans-Golgi Network Transport Vesicle Cytoplasmic Vesicle Insulin-responsive Compartment Neuron Projection Recycling Endosome Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Cellular_component Golgi Apparatus Synaptic Vesicle Endosome Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Molecular_function Protein Binding
	Biological Process	Vesicle Docking Involved In Exocytosis Protein Secretion Protein Kinase A Signaling Endosomal Transport Regulation Of Exocytosis Cortical Actin Cytoskeleton Organization Neuron Projection Development Endocytic Recycling Cellular Response To Insulin Stimulus Endothelial Cell Chemotaxis Trans-Golgi Network To Recycling Endosome Transport Golgi Vesicle Fusion To Target Membrane Bicellular Tight Junction Assembly Protein Localization To Plasma Membrane Establishment Of Sertoli Cell Barrier	Intracellular Protein Transport Vesicle-mediated Transport
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Intra-Golgi traffic Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Broad depression or schizophrenia ( 30626913) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Hip circumference adjusted for BMI ( 34021172) Obesity in adult survivors of childhood cancer not exposed to cranial radiation ( 25963547) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Uric acid levels ( 21294900)
Interacting Genes		11 interacting genes: APP MICALL1 PDE6D RAB11A RAB7A RAB8A RABGAP1L SMAD4 SMURF2 TGFBR1 VPS45	16 interacting genes: BCAR3 C1orf43 CASP8 H2AC18 IGF1R PAX2 PTPN1 RAB13 RB1CC1 RBSN RPRD2 SNTG1 STX16 SV2A VPS11 VPS18
Entrez ID		5872	11311
HPRD ID		04053	10301
Ensembl ID		ENSG00000143545	ENSG00000136631
Uniprot IDs		A0A087WWB9 P51153 Q504R6	A0A2R8YE10 B7Z360 B7Z5D4 Q9NRW7
PDB IDs
Enriched GO Terms of Interacting Partners?
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