RAB4A and KCTD7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		RAB4A	KCTD7
Description		RAB4A, member RAS oncogene family	potassium channel tetramerization domain containing 7
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Plasma Membrane Cytoplasmic Vesicle Membrane Early Endosome Membrane Vesicle Insulin-responsive Compartment Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome Postsynaptic Recycling Endosome Anchored Component Of Synaptic Vesicle Membrane	Cytoplasm Cytosol Plasma Membrane
	Molecular Function	ATPase Activator Activity GTPase Activity G Protein Activity Protein Binding GTP Binding GDP Binding Syntaxin Binding Ionotropic Glutamate Receptor Binding ATPase Binding	Protein Binding
	Biological Process	Protein Transport Antigen Processing And Presentation Regulation Of Endocytosis Rab Protein Signal Transduction Regulation Of Catalytic Activity	Cellular Potassium Ion Homeostasis Positive Regulation Of Transporter Activity Protein Homooligomerization Membrane Hyperpolarization Glutamate Homeostasis
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Synthesis of PIPs at the plasma membrane TBC/RABGAPs RAB geranylgeranylation MET receptor recycling	Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Aging ( 22773346) Leukoderma in response to rhododendrol ( 32558222) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Mercury levels ( 26025379) Response to antidepressants in depression ( 27622933)	Aortic root size ( 21223598) Cotinine glucuronidation ( 25293881) Estimated glomerular filtration rate ( 31152163)
Interacting Genes		33 interacting genes: ACTB APBB3 CD2AP CDK1 CHM DYNC1LI1 DYNLL1 EXOC5 FAM71C GDI2 GRIPAP1 HACE1 IDH3A KCTD7 KIF3B MAPK3 PIN1 PRKCI PTTG1IP RAB11FIP1 RAB7A RABAC1 RABEP1 RABEP2 RABGAP1 RABGEF1 RBSN RUFY1 SOD2 STX4 TP53 VPS52 ZNF830	41 interacting genes: ADAMTSL4 ATXN7L2 BAG4 CUL3 DVL3 EFHC2 GAS2L2 GORASP2 INCA1 INO80B KAT5 KRT75 KRTAP13-3 LNX1 MDFI MEOX1 MEOX2 NIF3L1 NTAQ1 NXF1 PARVG PAX6 PIN1 PPARA PRPF18 PRR22 PSMA1 RAB4A REL TCEA2 TCEANC TERF1 TRIM2 TRIM3 UBC VEZF1 ZNF417 ZNF438 ZNF474 ZNF552 ZNF587
Entrez ID		5867	154881
HPRD ID		01541	13770
Ensembl ID		ENSG00000168118	ENSG00000243335
Uniprot IDs		A0A024R3U9 A0A087WYT5 P20338	A0A024RDN7 Q96MP8
PDB IDs		1YU9 1Z0K 2BMD 2BME
Enriched GO Terms of Interacting Partners?
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