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QARS1 and SMN1
Number of citations of the paper that reports this interaction (PubMedID
21900206
)
136
Data Source:
BioGRID
(two hybrid)
QARS1
SMN1
Description
glutaminyl-tRNA synthetase 1
survival of motor neuron 1, telomeric
Image
GO Annotations
Cellular Component
Cytoplasm
Mitochondrial Matrix
Cytosol
Aminoacyl-tRNA Synthetase Multienzyme Complex
Protein-containing Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cajal Body
Nuclear Body
Z Disc
Axon
SMN Complex
SMN-Sm Protein Complex
Cytoplasmic Ribonucleoprotein Granule
Neuron Projection
Perikaryon
Gemini Of Coiled Bodies
Molecular Function
Glutamine-tRNA Ligase Activity
Protein Kinase Inhibitor Activity
Protein Binding
ATP Binding
Protein Kinase Binding
RNA Binding
Protein Binding
Identical Protein Binding
Biological Process
TRNA Aminoacylation For Protein Translation
Glutaminyl-tRNA Aminoacylation
Negative Regulation Of Protein Kinase Activity
Brain Development
Negative Regulation Of Stress-activated MAPK Cascade
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Apoptotic Signaling Pathway
Spliceosomal Complex Assembly
Spliceosomal SnRNP Assembly
DNA-templated Transcription, Termination
Nervous System Development
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Mitochondrial tRNA aminoacylation
snRNP Assembly
Drugs
Nusinersen
Diseases
GWAS
Interacting Genes
157 interacting genes:
ACTN2
ANXA7
APP
ASL
B9D2
BIRC7
CALCOCO2
CCDC33
CDK4
CDKN1A
CLTC
COG6
CPNE3
CTBP2
DISC1
DNM2
DPPA4
DTX2
DUSP11
EDC3
EFHC2
ESS2
FAM118B
FAM161A
FAM83A
GADD45A
GPBP1
GSK3B
GSTZ1
H2AX
HES7
HMG20A
HOXA1
IK
IKZF1
IRF1
KCNE3
KLC3
KRT36
LAMTOR3
LGALS9B
LGALS9C
LNX1
LZTS1
LZTS2
MAP3K5
MCCD1
MESD
MID2
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR155
MIR15A
MIR15B
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7G
MIRLET7I
NAB2
NEBL
NFKBID
NLGN3
NOXA1
PICK1
PIK3R3
PIN1
PPP1R32
PRDM6
PRRC2A
PTPN21
RARS1
REL
RNF11
SF3B4
SHLD1
SLA
SMAD9
SMN1
SORBS3
SP7
SPATC1L
SPDYE4
SPRED2
STK3
TADA2A
TCF12
TGM7
TK1
TLE5
TOPAZ1
TRAF2
TRAF4
TRIM27
TRIM35
TRIP13
TSC22D1
TTR
USHBP1
VPS37B
XIAP
ZMYND12
ZRANB1
165 interacting genes:
A1BG
A2M
ACTB
ACTL6B
ADAMTS10
AGAP1
ANXA2
APLP1
ARFGAP1
ATP5F1B
ATP6V1A
BAG6
BCL2
BLOC1S6
BYSL
C9orf72
CARHSP1
CCDC90B
CENPB
CHTOP
COIL
COL4A2
COL4A5
COPS6
CPNE6
CRIP2
CSAD
DDAH2
DDX20
DHX9
DMPK
DOCK7
DUS2
DYNC1I1
EEF1A1
EEF1A2
EHHADH
EIF3G
EXT2
EZH2
FAM20C
FAM9B
FBL
FGB
FLAD1
FNDC11
FUBP1
GAPDH
GAR1
GDF9
GEMIN2
GEMIN5
GEMIN7
H3-4
HADHB
HMGXB3
HNRNPR
HNRNPU
HNRNPUL1
IGHM
ILF3
IMMT
INPP5K
IQUB
ITCH
JADE1
KDM1A
KIF5A
KLHL5
KMT2B
KPNB1
KRTAP19-6
KRTAP19-7
KRTAP21-2
KRTAP6-1
KRTAP6-2
LENG8
LRIF1
LSM1
LSM10
LSM11
LSM2
LSM3
LSM4
LSM5
LSM6
LSM7
MAGED1
MAST2
MED31
MKI67
MPP1
MRPL37
MSH2
NGFR
NKIRAS2
NMT2
NRN1
NTAQ1
OSTF1
PDE4DIP
PKM
PLXNA3
POLR1C
POLR2A
POP7
PPIG
PSME1
QARS1
RBBP4
RBBP6
RBFOX2
RBM48
REX1BD
RN7SL1
RNU1-1
RNU11
RNU2-1
RNU4-1
RPL13
RPS2
RXRA
SCARNA1
SDF4
SELENOW
SEMA5B
SETDB1
SMC5
SMN2
SNORA81
SNRPB
SNRPD1
SNRPD2
SNRPD3
SNRPE
SNU13
SNUPN
SP110
SPANXN2
STRAP
STXBP2
STXBP3
SULT1A3
SUMO3
SYNCRIP
TAF1C
TERC
TIAL1
TLE1
TMSB4X
TP53
TRMT2A
TUBA1A
TUBB3
UCHL1
UNC119
USP4
VPS28
WDR18
WDR73
WIZ
ZBTB16
ZNF431
ZRANB2
ZXDC
Entrez ID
5859
6606
HPRD ID
07223
02646
Ensembl ID
ENSG00000172053
ENSG00000172062
Uniprot IDs
B7Z840
P47897
B4DP61
E7EQZ4
Q16637
PDB IDs
4R3Z
4YE6
4YE8
4YE9
1G5V
1MHN
2LEH
4A4E
4A4G
4GLI
4QQ6
5XJL
5XJQ
5XJR
5XJS
5XJT
5XJU
Enriched GO Terms of Interacting Partners
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