SMN1 and COIL

Number of citations of the paper that reports this interaction (PubMedID 11641277)
87

Data Source:
BioGRID (proximity labelling technology)
HPRD (in vitro, in vivo)

		SMN1	COIL
Description		survival of motor neuron 1, telomeric	coilin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Body Z Disc Axon SMN Complex SMN-Sm Protein Complex Cytoplasmic Ribonucleoprotein Granule Neuron Projection Perikaryon Gemini Of Coiled Bodies	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cajal Body Membrane Nuclear Body
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	Protein Binding Protein C-terminus Binding U1 SnRNA Binding U2 SnRNA Binding Identical Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly DNA-templated Transcription, Termination Nervous System Development	Spliceosomal SnRNP Assembly
Pathways		snRNP Assembly
Drugs		Nusinersen
Diseases
GWAS			Height ( 18391951)
Interacting Genes		165 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 AGAP1 ANXA2 APLP1 ARFGAP1 ATP5F1B ATP6V1A BAG6 BCL2 BLOC1S6 BYSL C9orf72 CARHSP1 CCDC90B CENPB CHTOP COIL COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CSAD DDAH2 DDX20 DHX9 DMPK DOCK7 DUS2 DYNC1I1 EEF1A1 EEF1A2 EHHADH EIF3G EXT2 EZH2 FAM20C FAM9B FBL FGB FLAD1 FNDC11 FUBP1 GAPDH GAR1 GDF9 GEMIN2 GEMIN5 GEMIN7 H3-4 HADHB HMGXB3 HNRNPR HNRNPU HNRNPUL1 IGHM ILF3 IMMT INPP5K IQUB ITCH JADE1 KDM1A KIF5A KLHL5 KMT2B KPNB1 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP6-1 KRTAP6-2 LENG8 LRIF1 LSM1 LSM10 LSM11 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAGED1 MAST2 MED31 MKI67 MPP1 MRPL37 MSH2 NGFR NKIRAS2 NMT2 NRN1 NTAQ1 OSTF1 PDE4DIP PKM PLXNA3 POLR1C POLR2A POP7 PPIG PSME1 QARS1 RBBP4 RBBP6 RBFOX2 RBM48 REX1BD RN7SL1 RNU1-1 RNU11 RNU2-1 RNU4-1 RPL13 RPS2 RXRA SCARNA1 SDF4 SELENOW SEMA5B SETDB1 SMC5 SMN2 SNORA81 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNU13 SNUPN SP110 SPANXN2 STRAP STXBP2 STXBP3 SULT1A3 SUMO3 SYNCRIP TAF1C TERC TIAL1 TLE1 TMSB4X TP53 TRMT2A TUBA1A TUBB3 UCHL1 UNC119 USP4 VPS28 WDR18 WDR73 WIZ ZBTB16 ZNF431 ZRANB2 ZXDC	84 interacting genes: ACTN1 ACTN2 ACTN4 ADAMTS12 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP C9orf72 CCDC136 CCDC159 CCDC57 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 DYNC2I2 ELOA2 FGF12 FHL5 FXR1 FXR2 GCC1 HSF2BP KALRN KAZN KDM1A KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MCRS1 MYO15B MYO5B NFU1 NIF3L1 NKAPD1 NOLC1 NTAQ1 NUDT18 OGT PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 PLOD3 POLR2L POLR3C PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 SPANXN2 SRPK2 TAF9 TCAF1 TFCP2 TGS1 TSPYL2 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		6606	8161
HPRD ID		02646	02605
Ensembl ID		ENSG00000172062	ENSG00000121058
Uniprot IDs		B4DP61 E7EQZ4 Q16637	P38432
PDB IDs		1G5V 1MHN 2LEH 4A4E 4A4G 4GLI 4QQ6 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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