PYCR1 and CDK2AP2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

		PYCR1	CDK2AP2
Description		pyrroline-5-carboxylate reductase 1	cyclin dependent kinase 2 associated protein 2
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm Microtubule
	Molecular Function	Pyrroline-5-carboxylate Reductase Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Proline Biosynthetic Process Cellular Response To Oxidative Stress Regulation Of Mitochondrial Membrane Potential L-proline Biosynthetic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death	Regulation Of Microtubule Cytoskeleton Organization Regulation Of Stem Cell Division Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Glutamate and glutamine metabolism
Drugs		NADH Proline
Diseases
GWAS
Interacting Genes		7 interacting genes: BNIPL CDK2AP2 FXR1 HNRNPD NUDT21 SIRT3 TNPO2	17 interacting genes: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS1 YIF1A ZBTB48
Entrez ID		5831	10263
HPRD ID		01528	13242
Ensembl ID		ENSG00000183010	ENSG00000167797
Uniprot IDs		A0A024R8U9 E2QRB3 J3QL32 P32322 Q8TBX0	O75956 Q6IAV4
PDB IDs		2GER 2GR9 2GRA 2IZZ 5UAT 5UAU 5UAV 5UAW 5UAX 6XOZ 6XP0 6XP1 6XP2 6XP3	2M1L
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?