CXCL16 and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CXCL16	KIR2DL3
Description		C-X-C motif chemokine ligand 16	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Low-density Lipoprotein Particle Receptor Activity Scavenger Receptor Activity Chemokine Activity	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Receptor-mediated Endocytosis Chemotaxis Signal Transduction T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor	Immune Response
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Blood protein levels in cardiovascular risk ( 28369058)
Interacting Genes		64 interacting genes: ADAMTSL4 APP AQP2 AQP6 AQP9 ARL13B ATP6V0E1 BIK CARD10 CCDC70 CD53 CERS4 CLDN7 CREB3L1 CXCR6 CYSRT1 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GORAB GPR42 HHATL HOXA1 KASH5 KIR2DL3 KRT31 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP5-9 LHFPL5 LMNA MDFI MFF MTUS2 MUC1 NBPF19 NEMP1 NOTCH2NLA PEX12 SAR1A SLC16A2 SLC18A1 SLC39A1 SPN SSMEM1 STX1A TAB1 TGM1 TLCD4 TMEM139 TMEM14B TMEM237 TMEM239 TMEM35A TMX2 TSPAN12	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		58191	3804
HPRD ID		16103	10383
Ensembl ID		ENSG00000161921	ENSG00000243772
Uniprot IDs		Q9H2A7	E3NZD8 P43628
PDB IDs			1B6U 6PAG
Enriched GO Terms of Interacting Partners?
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