PTS and DDX10

		PTS	DDX10
Description		6-pyruvoyltetrahydropterin synthase	DEAD-box helicase 10
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Nucleus
	Molecular Function	6-pyruvoyltetrahydropterin Synthase Activity Protein Binding Identical Protein Binding Metal Ion Binding	RNA Binding RNA Helicase Activity ATP Binding ATP Hydrolysis Activity
	Biological Process	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development	RRNA Processing Anterior Head Development
Pathways		Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs		Mycophenolate mofetil Biopterin
Diseases
GWAS		Heel bone mineral density ( 30598549) Objective response to lithium treatment ( 26503763)	Bipolar disorder ( 34099189) Knee osteoarthritis ( 28916551) Systolic blood pressure ( 27841878)
Interacting Genes		13 interacting genes: AP2M1 ATM COIL DDIT4L DDX10 FNDC5 FXR2 LNX1 NTAQ1 PBRM1 PRKG2 SDCBP THAP10	16 interacting genes: ANTXR2 APP ARHGAP20 ARL2BP BCO2 CUL5 DES DSC3 FBXO7 HSPB2 IGFBP6 NPAT PGR PTS SIRPA SLN
Entrez ID		5805	1662
HPRD ID		11840	03138
Ensembl ID		ENSG00000150787	ENSG00000178105
Uniprot IDs		Q03393	Q13206
PDB IDs		3I2B	2PL3
Enriched GO Terms of Interacting Partners?
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