PLEKHA2 and SNTG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHA2	SNTG1
Description		pleckstrin homology domain containing A2	syntrophin gamma 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex	Intracellular Anatomical Structure Nucleus Cytoplasm Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Ruffle Membrane
	Molecular Function	Fibronectin Binding Protein Binding Lipid Binding PDZ Domain Binding Laminin Binding Phosphatidylinositol-3,4-bisphosphate Binding	Actin Binding Structural Molecule Activity Protein Binding Protein C-terminus Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion	Cell Communication
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 31211820) Monocyte percentage of white cells ( 32888494)	Abstraction and mental flexibility ( 31596458) Age at first sexual intercourse ( 34211149) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Interleukin-6 levels ( 22205395) Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Pulmonary function ( 17903307) Pulse pressure ( 27841878) Remission after SSRI treatment in MDD or openness ( 29559929) Response to SSRI in MDD or openness ( 29559929) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		19 interacting genes: COG6 DLG2 DLG3 EGLN3 FHL5 GIPC1 GIPC2 GIPC3 GOLGA2 HSF2BP KANK2 LNX1 M1AP MPDZ PLEKHA1 PTPN13 SNTG1 TEPSIN TRIM23	15 interacting genes: ADRA1D DGKZ DMD DTNA DTNB FGF2 KCNA4 PLEKHA1 PLEKHA2 SNAP23 STXBP3 TGFBR1 UBC VPS45 VTN
Entrez ID		59339	54212
HPRD ID			16373
Ensembl ID		ENSG00000169499	ENSG00000147481
Uniprot IDs		A0A087WZ32 A8K727 Q9HB19	A0A024R7Y0 A0A2R8Y5T2 A0A2R8Y631 B2RA84 Q9NSN8
PDB IDs
Enriched GO Terms of Interacting Partners?
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