PTPN4 and ZZEF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PTPN4	ZZEF1
Description		protein tyrosine phosphatase non-receptor type 4	zinc finger ZZ-type and EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding Cytoskeletal Protein Binding	Calcium Ion Binding Zinc Ion Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Toll Like Receptor 4 (TLR4) Cascade Interleukin-37 signaling MECP2 regulates neuronal receptors and channels
Drugs		Alendronic acid
Diseases
GWAS		Lymphocyte counts ( 32888494)	Anti-saccade response ( 29064472) Diastolic blood pressure ( 27841878) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Glucose homeostasis traits ( 25524916) Heel bone mineral density ( 30598549) Platelet distribution width ( 32888494) Refractive error ( 32231278) Schizophrenia ( 34099189) Type 2 diabetes ( 28566273 30054458 30297969 29632382 30718926) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		12 interacting genes: ATRX CRK EEF1A1 EEF1G GRID2 GRIN2A KAT5 LPL MAPK12 PRSS1 TK1 ZZEF1	4 interacting genes: HSPB3 PHYHIP PTPN4 SKIL
Entrez ID		5775	23140
HPRD ID		01471	15906
Ensembl ID		ENSG00000088179	ENSG00000074755
Uniprot IDs		P29074	O43149
PDB IDs		2CS5 2I75 2VPH 3NFK 3NFL 5EYZ 5EZ0
Enriched GO Terms of Interacting Partners?
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