PPP4R4 and PPP4C

Number of citations of the paper that reports this interaction (PubMedID 28514442)
406

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PPP4R4	PPP4C
Description		protein phosphatase 4 regulatory subunit 4	protein phosphatase 4 catalytic subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein Serine/threonine Phosphatase Complex	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Blastocyst Hatching Negative Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Protein Serine/threonine Phosphatase Activity	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling
Pathways			Processing of DNA double-strand break ends
Drugs
Diseases
GWAS		Blood protein levels ( 29875488) Chronic obstructive pulmonary disease ( 28166215) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)	Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Eosinophil percentage of white cells ( 32888494) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)
Interacting Genes		1 interacting genes: PPP4C	21 interacting genes: CCDC6 DHX38 GPANK1 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6
Entrez ID		57718	5531
HPRD ID		13878	03615
Ensembl ID		ENSG00000119698	ENSG00000149923
Uniprot IDs		Q6NUP7	A0A024R625 P60510
PDB IDs
Enriched GO Terms of Interacting Partners?
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