SLC7A14 and C1GALT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		SLC7A14	C1GALT1
Description		solute carrier family 7 member 14	core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Amino Acid Transmembrane Transporter Activity	Protein Binding Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Activity Metal Ion Binding
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport	Angiogenesis Kidney Development O-glycan Processing, Core 1 Cell Differentiation
Pathways			Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)	Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 29875488) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Daytime sleep phenotypes ( 27126917) Diastolic blood pressure ( 30224653) Erosive tooth wear (severe vs non-severe) ( 29898447) FEV1 ( 30804560) Lung function (FEV1/FVC) ( 28166213 30804560) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Multiple sclerosis (severity) ( 19010793) Night sleep phenotypes ( 27126917) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Serum galactose-deficient IgA1 levels ( 28187132) Serum galactose-deficient IgA1 levels in IgA nephropathy ( 33593824) Smooth-surface caries ( 24556642) Systolic blood pressure ( 26969751) Visceral adipose tissue adjusted for BMI ( 22589738)
Interacting Genes		47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1	32 interacting genes: ANKS6 ARL13B C1GALT1C1 CD79A CPLX4 ELOVL4 FAM209A FAM210B GJA8 GJB1 GJB5 GPR101 GPR151 GPR42 GPRC5D GPX8 GSDME LEPROT LEUTX LHFPL5 MUC1 PIGP RETREG3 SLC14A1 SLC1A1 SLC7A14 STX1A TMEM14B TMEM237 TMEM52B TRAF6 XRN1
Entrez ID		57709	56913
HPRD ID		17222	16631
Ensembl ID		ENSG00000013293	ENSG00000106392
Uniprot IDs		Q8TBB6	A0A024RA32 Q9NS00
PDB IDs
Enriched GO Terms of Interacting Partners?
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