MRTFA and KDM3A

Number of citations of the paper that reports this interaction (PubMedID 17991879)
50

Data Source:
BioGRID (pull down)

		MRTFA	KDM3A
Description		myocardin related transcription factor A	lysine demethylase 3A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Transcription Coactivator Activity Actin Binding Actin Monomer Binding Protein Binding Leucine Zipper Domain Binding	Transcription Coregulator Activity Iron Ion Binding Protein Binding Chromatin DNA Binding Histone H3-methyl-lysine-9 Demethylase Activity Androgen Receptor Binding Dioxygenase Activity
	Biological Process	Positive Regulation Of Transcription Via Serum Response Element Binding Actin Cytoskeleton Organization Wound Healing, Spreading Of Cells Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation Positive Regulation Of Pri-miRNA Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Spermatid Nucleus Elongation Hormone-mediated Signaling Pathway Androgen Receptor Signaling Pathway Histone H3-K9 Demethylation Histone H3-K9 Dimethylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Formaldehyde Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Leukemia Inhibitory Factor Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation
Pathways		SUMOylation of transcription cofactors RHO GTPases Activate Formins	HDMs demethylate histones NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs		Latrunculin B
Diseases
GWAS			Atrial fibrillation ( 29892015) Glomerular filtration rate in chronic kidney disease ( 26420894) Ovarian cancer ( 30557369)
Interacting Genes		10 interacting genes: KDM3A MRTFB MVP MYOCD NCOA3 SMARCA4 SRF SUMO1 TRIM54 UBE2I	6 interacting genes: ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Entrez ID		57591	55818
HPRD ID		10445	11054
Ensembl ID		ENSG00000196588	ENSG00000115548
Uniprot IDs		A4FUJ8 E7ER32 Q969V6 W0Z7M9	Q9Y4C1
PDB IDs		2KVU 2KW9
Enriched GO Terms of Interacting Partners?
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