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KDM3A

Description lysine demethylase 3A
Image No pdb structure
GO Annotations Cellular Component
  • Histone Deacetylase Complex
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Membrane
Molecular Function
  • Transcription Coregulator Activity
  • Iron Ion Binding
  • Protein Binding
  • Chromatin DNA Binding
  • Histone H3-methyl-lysine-9 Demethylase Activity
  • Androgen Receptor Binding
  • Dioxygenase Activity
Biological Process
  • Regulation Of Transcription By RNA Polymerase II
  • Spermatid Nucleus Elongation
  • Hormone-mediated Signaling Pathway
  • Androgen Receptor Signaling Pathway
  • Histone H3-K9 Demethylation
  • Histone H3-K9 Dimethylation
  • Positive Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Formaldehyde Biosynthetic Process
  • Negative Regulation Of Histone H3-K9 Methylation
  • Positive Regulation Of Cold-induced Thermogenesis
  • Cellular Response To Leukemia Inhibitory Factor
  • Regulation Of Stem Cell Population Maintenance
  • Regulation Of Stem Cell Differentiation
Pathways
  • HDMs demethylate histones
  • NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS
  • Atrial fibrillation ( 29892015)
  • Glomerular filtration rate in chronic kidney disease ( 26420894)
  • Ovarian cancer ( 30557369)
Interacting Genes 6 interacting genes: ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Entrez ID 55818
HPRD ID 11054
Ensembl ID ENSG00000115548
Uniprot IDs Q9Y4C1
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025