AHRR and ADCY2

		AHRR	ADCY2
Description		aryl-hydrocarbon receptor repressor	adenylate cyclase 2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol Aryl Hydrocarbon Receptor Complex	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Dendrite Membrane Raft
	Molecular Function	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Nuclear Receptor Activity Protein Binding Protein Dimerization Activity	Magnesium Ion Binding Adenylate Cyclase Activity ATP Binding Adenylate Cyclase Binding Manganese Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Xenobiotic Metabolic Process Intracellular Receptor Signaling Pathway	CAMP Biosynthetic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway CAMP-mediated Signaling Cellular Response To Forskolin
Pathways		PPARA activates gene expression Phase I - Functionalization of compounds Endogenous sterols Xenobiotics Aryl hydrocarbon receptor signalling	Glucagon signaling in metabolic regulation PKA activation PKA activation in glucagon signalling Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Adenylate cyclase inhibitory pathway G alpha (s) signalling events G alpha (s) signalling events G alpha (i) signalling events G alpha (z) signalling events G alpha (z) signalling events Vasopressin regulates renal water homeostasis via Aquaporins Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis
Drugs			Colforsin 2',5'-DIDEOXY-ADENOSINE 3'-MONOPHOSPHATE Aurothioglucose
Diseases
GWAS		Breast cancer ( 29059683) Cystic fibrosis severity ( 21602797) Estimated glomerular filtration rate ( 31015462) Eye color ( 33692100) Fat distribution (HIV) ( 21897333) Hemoglobin levels ( 32327693) Hip circumference adjusted for BMI ( 34021172) Intraocular pressure ( 29617998) Systolic blood pressure ( 30224653)	Anxiety and stress-related disorders ( 31116379) Atorvastatin-induced myopathy ( 31220337) Bipolar disorder ( 24618891 31043756) Bipolar disorder (age of onset <21) or attention deficit hyperactivity disorder ( 27890468) Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Bipolar I disorder ( 31043756) Caffeine consumption from coffee ( 33287642) Caffeine consumption from coffee or tea ( 33287642) Capecitabine sensitivity ( 22864933) Coffee consumption ( 31046077) Cognitive decline rate in late mild cognitive impairment ( 26252872) Food addiction ( 27106561) LDL cholesterol levels in HIV infection ( 33109212) Mean arterial pressure (alcohol consumption interaction) ( 24376456) Oropharynx cancer ( 27749845) Pars opercularis volume ( 31530798) Plasma factor VII activating protease levels ( 30070759) Posterior-cingulate cortex volume ( 31530798) Smoking status (heavy vs never) ( 26423011) Visceral fat ( 22589738)
Interacting Genes		3 interacting genes: ADCY2 ARNT SLC6A3	14 interacting genes: ADCY1 ADCY5 AHRR CDH18 DRD4 F2RL1 GCDH GNAS GNG2 ISL1 NUF2 OBP2A RDH12 SLC9A3
Entrez ID		57491	108
HPRD ID		07356	00052
Ensembl ID		ENSG00000063438	ENSG00000078295
Uniprot IDs		A9YTQ3	Q08462 Q71UM8
PDB IDs		5Y7Y
Enriched GO Terms of Interacting Partners?
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