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PTBP1 and MIR34A
Number of citations of the paper that reports this interaction (PubMedID
28431233
)
92
Data Source:
BioGRID
(unspecified method)
PTBP1
MIR34A
Description
polypyrimidine tract binding protein 1
microRNA 34a
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Membrane
Extracellular Exosome
Extracellular Exosome
Extracellular Vesicle
Molecular Function
RNA Binding
MRNA Binding
Protein Binding
Poly-pyrimidine Tract Binding
Pre-mRNA Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Negative Regulation Of RNA Splicing
Positive Regulation Of Protein Dephosphorylation
Regulation Of RNA Splicing
Regulation Of Cell Differentiation
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Muscle Cell Differentiation
Positive Regulation Of Calcineurin-NFAT Signaling Cascade
IRES-dependent Viral Translational Initiation
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Negative Regulation Of Transmembrane Transport
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Regulation Of Cell Cycle
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
Pathways
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS
Alanine aminotransferase levels (
33547301
34315874
)
Aspartate aminotransferase levels (
34315874
)
Hematocrit (
32888494
27863252
)
Hemoglobin (
32888494
)
Hemoglobin concentration (
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Vertical cup-disc ratio (multi-trait analysis) (
31959993
)
Height (
31562340
)
Lean body mass (
28552196
)
Interacting Genes
103 interacting genes:
APBB1
APP
CALCOCO2
CASP3
FUS
H3-4
HIF1A
HMGA1
HMGA2
HNRNPAB
HNRNPL
IL7R
LINC00839
LINC01554
MARK4
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NONO
OGT
PCBP1
PCBP2
PCBP3
PRKACA
QKI
RAVER1
RAVER2
RBFOX2
RBM10
SFPQ
SNRPA
SRPK2
SUMO2
ZMYM2
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
Entrez ID
5725
407040
HPRD ID
02823
Ensembl ID
ENSG00000011304
ENSG00000284357
Uniprot IDs
A0A7I2V621
P26599
PDB IDs
1QM9
1SJQ
1SJR
2AD9
2ADB
2ADC
2EVZ
2N3O
3ZZY
3ZZZ
Enriched GO Terms of Interacting Partners
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