PTAFR and ARR3

Number of citations of the paper that reports this interaction (PubMedID 11729201)
16

Data Source:
HPRD (in vitro, in vivo)

		PTAFR	ARR3
Description		platelet activating factor receptor	arrestin 3
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Secretory Granule Membrane Tertiary Granule Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Synapse
	Molecular Function	Lipopolysaccharide Binding Lipopolysaccharide Immune Receptor Activity G Protein-coupled Receptor Activity Platelet Activating Factor Receptor Activity Phospholipid Binding G Protein-coupled Purinergic Nucleotide Receptor Activity Mitogen-activated Protein Kinase Binding	G Protein-coupled Receptor Binding Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Positive Regulation Of Cellular Extravasation Regulation Of Transcription By RNA Polymerase II Chemotaxis Inflammatory Response Immune Response G Protein-coupled Receptor Signaling Pathway Parturition Response To Symbiotic Bacterium Positive Regulation Of Phospholipase C Activity Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Inositol Trisphosphate Biosynthetic Process G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway Positive Regulation Of Neutrophil Degranulation Transcytosis Positive Regulation Of Translation Negative Regulation Of Blood Pressure Phosphatidylinositol-mediated Signaling Positive Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Inositol Phosphate Biosynthetic Process Cellular Response To Gravity Cellular Response To CAMP Cellular Response To Fatty Acid Response To Dexamethasone Positive Regulation Of Voltage-gated Chloride Channel Activity Positive Regulation Of Leukocyte Tethering Or Rolling Positive Regulation Of Sensory Perception Of Pain Positive Regulation Of Transcytosis Positive Regulation Of Maternal Process Involved In Parturition Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction Cellular Response To 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	Regulation Of Protein Phosphorylation G Protein-coupled Receptor Internalization Signal Transduction Visual Perception
Pathways		Class A/1 (Rhodopsin-like receptors) G alpha (q) signalling events Interleukin-10 signaling Neutrophil degranulation Interferon gamma signaling
Drugs		Platelet Activating Factor Etizolam Rupatadine
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825)
Interacting Genes		19 interacting genes: ARR3 ARRB2 CALM1 GORAB GRIN1 GTPBP3 IFITM3 MBP MFSD3 PLLP PPM1J PRNP RGS4 RHBDD2 SERINC5 SPATA24 TMEM120A TMX2 TYK2	20 interacting genes: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 DVL2 FSHR GNMT MAP2K7 MARCHF8 OPN1MW OPN4 PLK4 PTAFR RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		5724	407
HPRD ID		01422	02358
Ensembl ID		ENSG00000169403	ENSG00000120500
Uniprot IDs		A8K7N8 P25105	P36575
PDB IDs		2B0X	1XEH 2A34
Enriched GO Terms of Interacting Partners?
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