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PTAFR
Description
platelet activating factor receptor
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Secretory Granule Membrane
Tertiary Granule Membrane
Molecular Function
Lipopolysaccharide Binding
Lipopolysaccharide Immune Receptor Activity
G Protein-coupled Receptor Activity
Platelet Activating Factor Receptor Activity
Phospholipid Binding
G Protein-coupled Purinergic Nucleotide Receptor Activity
Mitogen-activated Protein Kinase Binding
Biological Process
Positive Regulation Of Cellular Extravasation
Regulation Of Transcription By RNA Polymerase II
Chemotaxis
Inflammatory Response
Immune Response
G Protein-coupled Receptor Signaling Pathway
Parturition
Response To Symbiotic Bacterium
Positive Regulation Of Phospholipase C Activity
Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Tumor Necrosis Factor Production
Inositol Trisphosphate Biosynthetic Process
G Protein-coupled Purinergic Nucleotide Receptor Signaling Pathway
Positive Regulation Of Neutrophil Degranulation
Transcytosis
Positive Regulation Of Translation
Negative Regulation Of Blood Pressure
Phosphatidylinositol-mediated Signaling
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Inositol Phosphate Biosynthetic Process
Cellular Response To Gravity
Cellular Response To CAMP
Cellular Response To Fatty Acid
Response To Dexamethasone
Positive Regulation Of Voltage-gated Chloride Channel Activity
Positive Regulation Of Leukocyte Tethering Or Rolling
Positive Regulation Of Sensory Perception Of Pain
Positive Regulation Of Transcytosis
Positive Regulation Of Maternal Process Involved In Parturition
Positive Regulation Of Gastro-intestinal System Smooth Muscle Contraction
Cellular Response To 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
Pathways
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interleukin-10 signaling
Neutrophil degranulation
Interferon gamma signaling
Drugs
Platelet Activating Factor
Etizolam
Rupatadine
Diseases
GWAS
Blond vs. brown/black hair color (
30531825
)
Interacting Genes
19 interacting genes:
ARR3
ARRB2
CALM1
GORAB
GRIN1
GTPBP3
IFITM3
MBP
MFSD3
PLLP
PPM1J
PRNP
RGS4
RHBDD2
SERINC5
SPATA24
TMEM120A
TMX2
TYK2
Entrez ID
5724
HPRD ID
01422
Ensembl ID
ENSG00000169403
Uniprot IDs
A8K7N8
P25105
PDB IDs
2B0X
Enriched GO Terms of Interacting Partners
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