RTN4 and CERT1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		RTN4	CERT1
Description		reticulon 4	ceramide transporter 1
Image
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Postsynaptic Density Integral Component Of Endoplasmic Reticulum Membrane Cell Projection Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Membrane	Nucleoplasm Mitochondrion Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Ubiquitin Protein Ligase Binding Cadherin Binding	Protein Binding Kinase Activity Phosphatidylinositol-4-phosphate Binding Ceramide Binding Ceramide Transfer Activity Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Blastocyst Formation Apoptotic Process Axonal Fasciculation Positive Regulation Of Epithelial Cell Migration Cerebral Cortex Radial Glia-guided Migration Negative Regulation Of Cell Growth Negative Regulation Of Axon Extension Positive Regulation Of Mammary Gland Epithelial Cell Proliferation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Regulation Of Apoptotic Process Protein Stabilization Nuclear Pore Complex Assembly Positive Regulation Of Protein Kinase B Signaling Cardiac Epithelial To Mesenchymal Transition Protein Localization To Lysosome Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Cellular Sphingolipid Homeostasis Negative Regulation Of Amyloid-beta Formation Positive Regulation Of Protein Localization To Endoplasmic Reticulum Positive Regulation Of ERBB3 Signaling Pathway Endoplasmic Reticulum Tubular Network Membrane Organization Regulation Of Branching Morphogenesis Of A Nerve	Cell Morphogenesis In Utero Embryonic Development Heart Morphogenesis Ceramide Metabolic Process Muscle Contraction Immune Response Endoplasmic Reticulum Organization Signal Transduction Cell Population Proliferation Phosphorylation Response To Endoplasmic Reticulum Stress ER To Golgi Ceramide Transport Ceramide Transport Lipid Homeostasis Mitochondrion Morphogenesis Intermembrane Lipid Transfer Intermembrane Sphingolipid Transfer Ceramide 1-phosphate Transport
Pathways		Axonal growth inhibition (RHOA activation)
Drugs
Diseases
GWAS		Adult body size ( 32376654) Fasting glucose ( 34074324) Lymphocyte counts ( 32888494) Obesity (extreme) ( 19553259) Platelet count ( 32888494) Systolic blood pressure ( 30224653 32902719)
Interacting Genes		55 interacting genes: BAIAP2 BCL2 BCL2L1 BDKRB1 CCR4 CERT1 CGREF1 CHMP6 CHRM4 CLN8 CNTNAP1 CRMP1 CYSLTR2 DRD2 ERBB2 ERBB3 ERBB4 F2RL1 FXR2 GLP1R GPR35 HLA-DPB1 HTR2C IPP LAMA4 LINC01554 LMNA LRCH4 LRPAP1 MBP NAPA NR4A1 NRXN1 NSD1 OGT PLEKHF2 POT1 PPP1R21 PRR13 RAB33A RPS27 RTN3 RTN4IP1 RTN4R SNX1 SNX15 SPG21 STON1 SYT16 TERF1 TUBA4A UQCRC1 UQCRC2 WWP1 ZFYVE21	18 interacting genes: ACTL8 AQP2 ARL6IP1 BSND CBS COL4A3 CSNK1G2 FTSJ1 ITGB3BP MINAR1 PM20D2 POM121 REEP6 RTN3 RTN4 SMU1 STX2 TGM2
Entrez ID		57142	10087
HPRD ID		07259	05246
Ensembl ID		ENSG00000115310	ENSG00000113163
Uniprot IDs		Q9NQC3	A0A024RAJ5 A0A2R8Y7C5 Q9Y5P4
PDB IDs		2G31 2JV5	2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2RSG 2Z9Y 2Z9Z 3H3Q 3H3R 3H3S 3H3T 4HHV 5JJD 5ZYG 5ZYH 5ZYI 5ZYJ 5ZYK 5ZYL 5ZYM 6IEZ 6IF0 6J0O 6J81
Enriched GO Terms of Interacting Partners?
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