PNPLA2 and SERPINF1

Number of citations of the paper that reports this interaction (PubMedID 17032652)
113

Data Source:
BioGRID (pull down, pull down)

		PNPLA2	SERPINF1
Description		patatin like phospholipase domain containing 2	serpin family F member 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Membrane Integral Component Of Membrane	Extracellular Region Basement Membrane Extracellular Space Melanosome Axon Hillock Perinuclear Region Of Cytoplasm Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Lipoprotein Lipase Activity Triglyceride Lipase Activity Acylglycerol O-acyltransferase Activity Retinyl-palmitate Esterase Activity	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Diacylglycerol Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Triglyceride Catabolic Process Lipid Storage Lipid Droplet Organization Acylglycerol Acyl-chain Remodeling Retinol Metabolic Process Lipid Homeostasis	Kidney Development Aging Short-term Memory Response To Acidic PH Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Negative Regulation Of Endopeptidase Activity Positive Regulation Of Neuron Projection Development Negative Regulation Of Angiogenesis Ovulation Cycle Response To Arsenic-containing Substance Negative Regulation Of Inflammatory Response Positive Regulation Of Neurogenesis Retina Development In Camera-type Eye Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Cellular Response To Cobalt Ion Cellular Response To Retinoic Acid Cellular Response To Glucose Stimulus Cellular Response To Dexamethasone Stimulus Negative Regulation Of Neuron Death Response To Peptide
Pathways		Acyl chain remodeling of DAG and TAG Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Copper
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body shape index ( 34021172) HDL cholesterol levels ( 32203549) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Keratoconus ( 31855235) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Blood protein levels ( 30072576 29875488) Calcium levels ( 20705733)
Interacting Genes		10 interacting genes: ABHD5 ARFGEF2 CYTH2 FAF2 GBF1 MARK3 PHYHIP SERPINF1 SMAD9 UBE2R2	11 interacting genes: CSNK2A1 EPM2AIP1 IMPACT KDR LRP6 MLH1 MYOC NEDD4L PNPLA2 PTPN11 SGTB
Entrez ID		57104	5176
HPRD ID		11443	01408
Ensembl ID		ENSG00000177666	ENSG00000132386
Uniprot IDs		Q96AD5	A0A140VKF3 P36955
PDB IDs			1IMV
Enriched GO Terms of Interacting Partners?
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