NIT2 and TOMM70

		NIT2	TOMM70
Description		nitrilase family member 2	translocase of outer mitochondrial membrane 70
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Centrosome Cytosol Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Omega-amidase Activity 2-oxoglutaramate Amidase Activity	Protein Binding Protein Transmembrane Transporter Activity Mitochondrion Targeting Sequence Binding
	Biological Process	Oxaloacetate Metabolic Process Asparagine Metabolic Process Glutamine Metabolic Process	Activation Of Innate Immune Response Positive Regulation Of Defense Response To Virus By Host Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Positive Regulation Of Interferon-beta Production Regulation Of Apoptotic Process Protein Insertion Into Mitochondrial Inner Membrane Cellular Response To Virus
Pathways		Neutrophil degranulation	Mitochondrial protein import DDX58/IFIH1-mediated induction of interferon-alpha/beta PINK1-PRKN Mediated Mitophagy Ub-specific processing proteases
Drugs
Diseases
GWAS		Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: TOMM70	18 interacting genes: CTNNA2 DCBLD2 FOXC1 HSP90AA1 HSPA1A HSPA1B HSPB1 IRF3 KIF2C NIT2 OGT OR5K4 PRKN PSAP SNAPIN TBC1D23 TFG TMEM45A
Entrez ID		56954	9868
HPRD ID		17634	16194
Ensembl ID		ENSG00000114021	ENSG00000154174
Uniprot IDs		Q9NQR4 V9HW91	O94826
PDB IDs			7KDT
Enriched GO Terms of Interacting Partners?
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