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TOMM70

Description translocase of outer mitochondrial membrane 70
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Outer Membrane
  • Mitochondrial Outer Membrane Translocase Complex
  • Membrane
  • Integral Component Of Membrane
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • Protein Transmembrane Transporter Activity
  • Mitochondrion Targeting Sequence Binding
Biological Process
  • Activation Of Innate Immune Response
  • Positive Regulation Of Defense Response To Virus By Host
  • Protein Targeting To Mitochondrion
  • Protein Import Into Mitochondrial Matrix
  • Positive Regulation Of Interferon-beta Production
  • Regulation Of Apoptotic Process
  • Protein Insertion Into Mitochondrial Inner Membrane
  • Cellular Response To Virus
Pathways
  • Mitochondrial protein import
  • DDX58/IFIH1-mediated induction of interferon-alpha/beta
  • PINK1-PRKN Mediated Mitophagy
  • Ub-specific processing proteases
Drugs
Diseases
GWAS
Interacting Genes 18 interacting genes: CTNNA2 DCBLD2 FOXC1 HSP90AA1 HSPA1A HSPA1B HSPB1 IRF3 KIF2C NIT2 OGT OR5K4 PRKN PSAP SNAPIN TBC1D23 TFG TMEM45A
Entrez ID 9868
HPRD ID 16194
Ensembl ID ENSG00000154174
Uniprot IDs O94826
PDB IDs 7KDT
Enriched GO Terms of Interacting Partners?
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