LXN and ZKSCAN4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		LXN	ZKSCAN4
Description		latexin	zinc finger with KRAB and SCAN domains 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleoplasm
	Molecular Function	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)	Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Schizophrenia ( 30285260) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679	23 interacting genes: CABP5 IL36RN LXN MDM4 MEOX2 OGT OSGIN1 PGBD1 PSMA6 SCAND1 TIAM1 TRIM39 ZKSCAN7 ZNF24 ZNF397 ZNF446 ZNF483 ZNF496 ZSCAN20 ZSCAN21 ZSCAN22 ZSCAN30 ZSCAN32
Entrez ID		56925	387032
HPRD ID		14327	15768
Ensembl ID		ENSG00000079257	ENSG00000187626
Uniprot IDs		Q9BS40	A0A0S2Z658 B7Z7H3 Q969J2
PDB IDs		2BO9
Enriched GO Terms of Interacting Partners?
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