ASCL3 and HEMK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ASCL3	HEMK1
Description		achaete-scute family bHLH transcription factor 3	HemK methyltransferase family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin RNA Polymerase II Transcription Regulator Complex	Mitochondrion
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity	DNA Binding Protein Binding N-methyltransferase Activity Protein Methyltransferase Activity Protein-(glutamine-N5) Methyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	DNA Methylation Protein Methylation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Brain morphology (MOSTest) ( 32665545)	Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Cocaine dependence ( 31212010) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Height ( 28552196)
Interacting Genes		9 interacting genes: APP GTF2A1L HEMK1 ID1 MYOD1 TCF12 TCF3 TCF4 VPS37C	18 interacting genes: AKAP8L ASCL3 CDC23 CHN1 CTAG1A CTAG1B HEATR9 INCA1 KRTAP19-1 MAGED1 PEF1 POU2AF1 PSMB4 SHOX SOHLH1 SPRYD7 TUBGCP5 UBQLN2
Entrez ID		56676	51409
HPRD ID		18523	13645
Ensembl ID		ENSG00000176009	ENSG00000114735
Uniprot IDs		Q9NQ33	A0A140VK98 B2RA37 Q9Y5R4
PDB IDs
Enriched GO Terms of Interacting Partners?
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