HEMK1 and ASCL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HEMK1	ASCL3
Description		HemK methyltransferase family member 1	achaete-scute family bHLH transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Chromatin RNA Polymerase II Transcription Regulator Complex
	Molecular Function	DNA Binding Protein Binding N-methyltransferase Activity Protein Methyltransferase Activity Protein-(glutamine-N5) Methyltransferase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Protein Dimerization Activity
	Biological Process	DNA Methylation Protein Methylation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Cocaine dependence ( 31212010) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Height ( 28552196)	Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		18 interacting genes: AKAP8L ASCL3 CDC23 CHN1 CTAG1A CTAG1B HEATR9 INCA1 KRTAP19-1 MAGED1 PEF1 POU2AF1 PSMB4 SHOX SOHLH1 SPRYD7 TUBGCP5 UBQLN2	9 interacting genes: APP GTF2A1L HEMK1 ID1 MYOD1 TCF12 TCF3 TCF4 VPS37C
Entrez ID		51409	56676
HPRD ID		13645	18523
Ensembl ID		ENSG00000114735	ENSG00000176009
Uniprot IDs		A0A140VK98 B2RA37 Q9Y5R4	Q9NQ33
PDB IDs
Enriched GO Terms of Interacting Partners?
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