EIF5A2 and PTBP2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		EIF5A2	PTBP2
Description		eukaryotic translation initiation factor 5A2	polypyrimidine tract binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Pore Endoplasmic Reticulum Membrane Cytosol Intracellular Membrane-bounded Organelle	Nucleus
	Molecular Function	Translation Elongation Factor Activity Protein Binding Ribosome Binding	RNA Binding MRNA Binding
	Biological Process	Translational Elongation Spermatogenesis Polyamine Homeostasis Protein Transport Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination MRNA Transport	MRNA Processing RNA Splicing Negative Regulation Of RNA Splicing Regulation Of RNA Splicing
Pathways		Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		C-reactive protein levels ( 30388399) Urate levels ( 31578528)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Body size at age 10 ( 32376654) Chronotype ( 30696823) Daytime nap ( 33568662) Femoral neck bone mineral density and trunk fat mass adjusted by trunk lean mass ( 32239398) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 32239398 30944420) Waist circumference ( 25673412)
Interacting Genes		8 interacting genes: CDC23 DHPS HIF1A NIF3L1 PTBP2 RAB30 REL SDCBP	22 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 OGT PCBP3 PKN2 PUF60 QKI RBM10 RBM4 RBPMS2 SNRPA TOM1
Entrez ID		56648	58155
HPRD ID		10426	12233
Ensembl ID		ENSG00000163577	ENSG00000117569
Uniprot IDs		Q9GZV4	A0A6Q8PFE6 A0A7I2RVZ4 B4DSS8 B4DSU5 Q9UKA9
PDB IDs			2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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