KMT2E and IFT22

		KMT2E	IFT22
Description		lysine methyltransferase 2E (inactive)	intraflagellar transport 22
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Plasma Membrane Nuclear Body Nuclear Speck Protein-containing Complex Transcriptionally Active Chromatin	Centrosome Cilium Endomembrane System Intraciliary Transport Particle B Ciliary Tip
	Molecular Function	Protein Binding Histone-lysine N-methyltransferase Activity Enzyme Binding Methylated Histone Binding Metal Ion Binding	GTPase Activity GTP Binding
	Biological Process	Neutrophil Mediated Immunity DNA Methylation Chromatin Organization Cell Cycle Erythrocyte Differentiation Neutrophil Activation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Histone H3-K4 Trimethylation	Intracellular Protein Transport
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Autism spectrum disorder ( 30804558) Autism spectrum disorder or schizophrenia ( 28540026) General risk tolerance (MTAG) ( 30643258) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Neutrophil count ( 32888494) Schizophrenia ( 29483656)
Interacting Genes		12 interacting genes: ALKBH4 ASH2L ATP13A1 CDK1 CYP2C18 FIS1 IFT22 LAMTOR5 MAPRE2 NFE4 TRAPPC14 ZCWPW1	1 interacting genes: KMT2E
Entrez ID		55904	64792
HPRD ID		10528	15204
Ensembl ID		ENSG00000005483	ENSG00000128581
Uniprot IDs		Q8IZD2	A0A024QYT8 A0A024QYV3 Q9H7X7
PDB IDs		2LV9 4L58 5HT6
Enriched GO Terms of Interacting Partners?
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