LUC7L2 and ATF7IP

Number of citations of the paper that reports this interaction (PubMedID 15231748)
99

Data Source:
HPRD (two hybrid)

		LUC7L2	ATF7IP
Description		LUC7 like 2, pre-mRNA splicing factor	activating transcription factor 7 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	U1 SnRNP Nuclear Speck U2-type Prespliceosome	Nucleus Nucleoplasm Transcription Regulator Complex Cytosol Nuclear Body
	Molecular Function	RNA Binding MRNA Binding Protein Binding Enzyme Binding	Transcription Corepressor Activity Protein Binding
	Biological Process	MRNA Splice Site Selection	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Regulation Of Protein Stability Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Protein Stabilization Positive Regulation Of DNA Methylation-dependent Heterochromatin Assembly
Pathways			PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Left ventricular end-diastolic volume (MTAG) ( 33495596) Left ventricular end-systolic volume (MTAG) ( 33495596)	Breast cancer ( 24143190) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Height ( 31562340 33713608) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Leukocyte telomere length ( 32109421) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 28604728 28604732 23666240)
Interacting Genes		58 interacting genes: AIMP2 ALB ANTKMT APP APPBP2 ATF7IP ATRX CADPS CDC37 CDK4 CDK5RAP2 CEP126 CHD3 DZIP1 EXOC1 FXR1 GADD45G GSK3B HAP1 HDHD2 HOXA1 IKBKG ITPRID2 KLHL20 LPL MAN2A2 MAP1LC3B MEOX2 NAP1L5 NASP NAT9 NDEL1 NDUFA4L2 NEDD4 NFYA NKAP NSF NUTF2 OFD1 OGT PABPC4 PDPK1 PEA15 PIK3R3 PTCD3 PTN SAT1 SETDB1 SRRM4 SRSF6 SRSF7 SVIL ULK2 UNC119 WASHC3 YWHAG ZCCHC10 ZRSR2	70 interacting genes: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CREBBP CSPG4 DISC1 DMTF1 DNM2 EHMT2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO2 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		51631	55729
HPRD ID		17456	09811
Ensembl ID		ENSG00000146963	ENSG00000171681
Uniprot IDs		Q9Y383	A0A024RAY1 B3KNI7 B3KQF8 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?
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