NUP133 and CENPF

Number of citations of the paper that reports this interaction (PubMedID 17363900)
96

Data Source:
HPRD (two hybrid, in vivo)

		NUP133	CENPF
Description		nucleoporin 133	centromere protein F
Image			No pdb structure
GO Annotations	Cellular Component	Kinetochore Nuclear Envelope Nuclear Pore Cytosol Membrane Nuclear Pore Outer Ring Nuclear Membrane	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Outer Kinetochore Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Axoneme Nuclear Matrix Midbody Ciliary Basal Body Pronucleus Perinuclear Region Of Cytoplasm Ciliary Transition Fiber
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore	Chromatin Binding Protein Binding Microtubule Binding Protein C-terminus Binding Protein Homodimerization Activity Dynein Complex Binding DNA-binding Transcription Factor Binding
	Biological Process	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery MRNA Export From Nucleus Protein Import Into Nucleus Nuclear Pore Organization Poly(A)+ MRNA Export From Nucleus Neural Tube Development Neurogenesis Paraxial Mesoderm Development Somite Development Nephron Development	Mitotic Cell Cycle Kidney Development Chromosome Segregation Mitotic Spindle Assembly Checkpoint Signaling Muscle Organ Development Response To Xenobiotic Stimulus Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Ventricular System Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly DNA Biosynthetic Process
Pathways		ISG15 antiviral mechanism Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) RHO GTPases Activate Formins tRNA processing in the nucleus Mitotic Prometaphase HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Polo-like kinase mediated events Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Type 2 diabetes ( 32499647)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Lung function (FVC) ( 30061609) Response to antineoplastic agents ( 21659360) Serum immune biomarker levels ( 32066700)
Interacting Genes		5 interacting genes: CACNA1C CENPF NUP107 NUP98 TCAP	16 interacting genes: BRAP CENPE CHMP2B FNTA FNTB HSD11B1 IRF6 KLHL41 NDEL1 NUP133 PLOD2 SLC30A1 SLC4A1AP SNAP25 SVIL TOP3B
Entrez ID		55746	1063
HPRD ID		06354	02582
Ensembl ID		ENSG00000069248	ENSG00000117724
Uniprot IDs		Q8WUM0	P49454
PDB IDs		1XKS 3CQC 3CQG 3I4R 5A9Q
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?