CENPF and SLC4A1AP

		CENPF	SLC4A1AP
Description		centromere protein F	solute carrier family 4 member 1 adaptor protein
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Chromatin Spindle Pole Outer Kinetochore Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Centrosome Spindle Cytosol Axoneme Nuclear Matrix Midbody Ciliary Basal Body Pronucleus Perinuclear Region Of Cytoplasm Ciliary Transition Fiber	Nucleoplasm Cytoplasm Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Protein Binding Microtubule Binding Protein C-terminus Binding Protein Homodimerization Activity Dynein Complex Binding DNA-binding Transcription Factor Binding	MRNA Binding Protein Binding
	Biological Process	Mitotic Cell Cycle Kidney Development Chromosome Segregation Mitotic Spindle Assembly Checkpoint Signaling Muscle Organ Development Response To Xenobiotic Stimulus Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Regulation Of Striated Muscle Tissue Development Ventricular System Development Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cell Division Metaphase Plate Congression Kinetochore Assembly DNA Biosynthetic Process
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Polo-like kinase mediated events Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Lung function (FVC) ( 30061609) Response to antineoplastic agents ( 21659360) Serum immune biomarker levels ( 32066700)	Alzheimer's disease ( 22159054) Bipolar disorder ( 31043756) Breast size ( 22747683) L-selectin levels ( 25576479) Schizophrenia ( 26198764)
Interacting Genes		16 interacting genes: BRAP CENPE CHMP2B FNTA FNTB HSD11B1 IRF6 KLHL41 NDEL1 NUP133 PLOD2 SLC30A1 SLC4A1AP SNAP25 SVIL TOP3B	9 interacting genes: ADORA2A APP ATP5MG CENPF CSNK2A1 MFHAS1 SLC4A1 SRPK1 TCF4
Entrez ID		1063	22950
HPRD ID		02582	04038
Ensembl ID		ENSG00000117724	ENSG00000163798
Uniprot IDs		P49454	Q9BWU0
PDB IDs			4H87
Enriched GO Terms of Interacting Partners?
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