PRKACG and HMGN1

Number of citations of the paper that reports this interaction (PubMedID 11438671)
39

Data Source:
BioGRID (enzymatic study)

		PRKACG	HMGN1
Description		protein kinase cAMP-activated catalytic subunit gamma	high mobility group nucleosome binding domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Ciliary Base	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity AMP-activated Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding Protein Kinase A Regulatory Subunit Binding Protein Serine Kinase Activity	DNA Binding Chromatin Binding Protein Binding Nucleosomal DNA Binding
	Biological Process	Renal Water Homeostasis Protein Phosphorylation Spermatogenesis Male Gonad Development Protein Kinase A Signaling High-density Lipoprotein Particle Assembly	Pyrimidine Dimer Repair By Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair Chromatin Organization Regulation Of Transcription By RNA Polymerase II Response To UV-B Response To UV-C Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Development, Heterochronic Post-embryonic Camera-type Eye Morphogenesis Regulation Of Epithelial Cell Proliferation Positive Regulation Of NAD+ ADP-ribosyltransferase Activity
Pathways		PKA-mediated phosphorylation of CREB PKA-mediated phosphorylation of key metabolic factors Triglyceride catabolism PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Rap1 signalling Regulation of insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins VEGFA-VEGFR2 Pathway CREB1 phosphorylation through the activation of Adenylate Cyclase CREB1 phosphorylation through the activation of Adenylate Cyclase Degradation of GLI1 by the proteasome Degradation of GLI2 by the proteasome GLI3 is processed to GLI3R by the proteasome Hedgehog 'off' state CD209 (DC-SIGN) signaling MAPK6/MAPK4 signaling RET signaling HDL assembly ROBO receptors bind AKAP5 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism ADORA2B mediated anti-inflammatory cytokines production ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)	Apolipoprotein A1 levels ( 33730874) LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		5 interacting genes: CDK17 CETP HMGN1 TNP1 TNP2	26 interacting genes: CAMSAP3 CDC42 CHEK2 EP300 ETS2 GSK3A HMGN2 HPF1 IRF2 KLF13 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 TMEM121B YWHAZ
Entrez ID		5568	3150
HPRD ID		01483	01231
Ensembl ID		ENSG00000165059	ENSG00000205581
Uniprot IDs		P22612	P05114 Q6NSG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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