HMGN1 and NFE2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
361

Data Source:
BioGRID (two hybrid)

		HMGN1	NFE2
Description		high mobility group nucleosome binding domain 1	nuclear factor, erythroid 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm PML Body Protein-DNA Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Nucleosomal DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding Protein N-terminus Binding WW Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Pyrimidine Dimer Repair By Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair Chromatin Organization Regulation Of Transcription By RNA Polymerase II Response To UV-B Response To UV-C Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Development, Heterochronic Post-embryonic Camera-type Eye Morphogenesis Regulation Of Epithelial Cell Proliferation Positive Regulation Of NAD+ ADP-ribosyltransferase Activity	Nucleosome Disassembly Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Hemostasis Positive Regulation Of Transcription, DNA-templated
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 33730874) LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)	Chronotype ( 30696823) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean platelet volume ( 22139419 24026423) Mean spheric corpuscular volume ( 32888494) Meat-related diet ( 32066663) Platelet count ( 29403010 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 27863252) Red cell distribution width ( 28957414) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		26 interacting genes: CAMSAP3 CDC42 CHEK2 EP300 ETS2 GSK3A HMGN2 HPF1 IRF2 KLF13 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 TMEM121B YWHAZ	22 interacting genes: ATF4 BTRC CREBBP ELF5 HMGN1 ITCH KAT2B MAFF MAFG MAFK MAPK8 NEDD4 NFE2L2 NFE2L3 PEX14 PHYHIP PRIM1 SCAND1 SSX5 TXN WWP1 YAP1
Entrez ID		3150	4778
HPRD ID		01231	09030
Ensembl ID		ENSG00000205581	ENSG00000123405
Uniprot IDs		P05114 Q6NSG7	A8K3E0 Q16621
PDB IDs			1LVX 2KZ5
Enriched GO Terms of Interacting Partners?
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