HIF1AN and ANKK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HIF1AN	ANKK1
Description		hypoxia inducible factor 1 subunit alpha inhibitor	ankyrin repeat and kinase domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Cell Projection
	Molecular Function	Notch Binding Protein Binding Ferrous Iron Binding Zinc Ion Binding 2-oxoglutarate-dependent Dioxygenase Activity Oxygen Sensor Activity Carboxylic Acid Binding Peptidyl-histidine Dioxygenase Activity Peptidyl-asparagine 3-dioxygenase Activity Protein Homodimerization Activity NF-kappaB Binding Ankyrin Repeat Binding Hypoxia-inducible Factor-asparagine Oxygenase Activity	Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Peptidyl-histidine Hydroxylation Peptidyl-aspartic Acid Hydroxylation Peptidyl-asparagine Hydroxylation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Vasculogenesis	Protein Phosphorylation Regulation Of Cell Cycle Process
Pathways		Cellular response to hypoxia
Drugs		D-tartaric acid N-(carboxycarbonyl)-D-phenylalanine	Fostamatinib
Diseases
GWAS		Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303)	Alcohol consumption (drinks per week) ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Experiencing mood swings ( 29500382)
Interacting Genes		19 interacting genes: ANKK1 ANKRD12 ANKRD37 ANKRD50 ASB13 ASB4 ASB7 ASB9 FBF1 HDAC1 HDAC2 HDAC3 HIF1A INVS NAA10 SIAH1 TP53BP2 UACA VHL	6 interacting genes: C12orf57 C2CD6 CHN1 CHN2 HIF1AN YEATS4
Entrez ID		55662	255239
HPRD ID		09426	10580
Ensembl ID		ENSG00000166135	ENSG00000170209
Uniprot IDs		Q9NWT6	Q8NFD2
PDB IDs		1H2K 1H2L 1H2M 1H2N 1IZ3 1MZE 1MZF 1YCI 2CGN 2CGO 2ILM 2W0X 2WA3 2WA4 2XUM 2Y0I 2YC0 2YDE 3D8C 3KCX 3KCY 3OD4 3P3N 3P3P 4AI8 4B7E 4B7K 4BIO 4JAA 4NR1 4Z1V 4Z2W 5JWK 5JWL 5JWP 5OP6 5OP8 5OPC 6H9J 6HA6 6HC8 6HKP 6HL5 6HL6 6RUJ
Enriched GO Terms of Interacting Partners?
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