ANKK1 and HIF1AN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ANKK1	HIF1AN
Description		ankyrin repeat and kinase domain containing 1	hypoxia inducible factor 1 subunit alpha inhibitor
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cell Projection	Nucleus Nucleoplasm Cytoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding ATP Binding Protein Serine Kinase Activity	Notch Binding Protein Binding Ferrous Iron Binding Zinc Ion Binding 2-oxoglutarate-dependent Dioxygenase Activity Oxygen Sensor Activity Carboxylic Acid Binding Peptidyl-histidine Dioxygenase Activity Peptidyl-asparagine 3-dioxygenase Activity Protein Homodimerization Activity NF-kappaB Binding Ankyrin Repeat Binding Hypoxia-inducible Factor-asparagine Oxygenase Activity
	Biological Process	Protein Phosphorylation Regulation Of Cell Cycle Process	Peptidyl-histidine Hydroxylation Peptidyl-aspartic Acid Hydroxylation Peptidyl-asparagine Hydroxylation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Vasculogenesis
Pathways			Cellular response to hypoxia
Drugs		Fostamatinib	D-tartaric acid N-(carboxycarbonyl)-D-phenylalanine
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Experiencing mood swings ( 29500382)	Body mass index ( 28892062 25673413) Brain morphology (MOSTest) ( 32665545) Cerebrospinal fluid t-tau:AB1-42 ratio ( 30153862) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 28298293 23362303)
Interacting Genes		6 interacting genes: C12orf57 C2CD6 CHN1 CHN2 HIF1AN YEATS4	19 interacting genes: ANKK1 ANKRD12 ANKRD37 ANKRD50 ASB13 ASB4 ASB7 ASB9 FBF1 HDAC1 HDAC2 HDAC3 HIF1A INVS NAA10 SIAH1 TP53BP2 UACA VHL
Entrez ID		255239	55662
HPRD ID		10580	09426
Ensembl ID		ENSG00000170209	ENSG00000166135
Uniprot IDs		Q8NFD2	Q9NWT6
PDB IDs			1H2K 1H2L 1H2M 1H2N 1IZ3 1MZE 1MZF 1YCI 2CGN 2CGO 2ILM 2W0X 2WA3 2WA4 2XUM 2Y0I 2YC0 2YDE 3D8C 3KCX 3KCY 3OD4 3P3N 3P3P 4AI8 4B7E 4B7K 4BIO 4JAA 4NR1 4Z1V 4Z2W 5JWK 5JWL 5JWP 5OP6 5OP8 5OPC 6H9J 6HA6 6HC8 6HKP 6HL5 6HL6 6RUJ
Enriched GO Terms of Interacting Partners?
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