PNRC2 and GALK1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

		PNRC2	GALK1
Description		proline rich nuclear receptor coactivator 2	galactokinase 1
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GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Golgi Apparatus Cytosol	Cytoplasm Cytosol Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Galactokinase Activity Protein Binding ATP Binding Galactose Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-independent Decapping Of Nuclear-transcribed MRNA	Galactose Metabolic Process Galactose Catabolic Process Galactitol Metabolic Process Carbohydrate Phosphorylation Glycolytic Process From Galactose
Pathways		Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Defective GALK1 can cause Galactosemia II (GALCT2) Galactose catabolism
Drugs			Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Obesity-related traits ( 23251661)	Alanine aminotransferase levels ( 33547301) White blood cell count ( 32888494)
Interacting Genes		23 interacting genes: APP AR BANP DCP1A ESR1 ESR2 ESRRA ESRRG FBXO7 GALK1 GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SPAG9 XRCC6 ZBTB16 ZBTB48	4 interacting genes: APP PNRC2 SPATA13 SUMO2
Entrez ID		55629	2584
HPRD ID		17871	05057
Ensembl ID		ENSG00000189266	ENSG00000108479
Uniprot IDs		Q9NPJ4	P51570 V9HWE7
PDB IDs		4B6H 5KQ1 5KQ4	1WUU 1YH7 6GR2 6Q3W 6Q3X 6Q8Z 6Q90 6Q91 6QJE 6ZGV 6ZGW 6ZGX 6ZGY 6ZGZ
Enriched GO Terms of Interacting Partners?
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