GALK1 and SPATA13

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		GALK1	SPATA13
Description		galactokinase 1	spermatogenesis associated 13
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Lamellipodium Filopodium Ruffle Membrane
	Molecular Function	Galactokinase Activity Protein Binding ATP Binding Galactose Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Galactose Metabolic Process Galactose Catabolic Process Galactitol Metabolic Process Carbohydrate Phosphorylation Glycolytic Process From Galactose	Cell Migration Lamellipodium Assembly Regulation Of Cell Migration Filopodium Assembly Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Defective GALK1 can cause Galactosemia II (GALCT2) Galactose catabolism	CDC42 GTPase cycle RAC1 GTPase cycle
Drugs		Phosphoaminophosphonic Acid-Adenylate Ester
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) White blood cell count ( 32888494)	Airflow obstruction ( 22837378) Autoimmune thyroid disease ( 32581359) Cerebral cortical growth ( 29682794) Depression and alcohol dependence ( 22064162) Heel bone mineral density ( 30598549) Hypothyroidism ( 27182965) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Orofacial clefts ( 22419666) Plateletcrit ( 32888494) Thyroid stimulating hormone levels ( 30367059 32769997) Tumor necrosis factor receptor II (red blood cell fatty acid level interaction) ( 28820441)
Interacting Genes		4 interacting genes: APP PNRC2 SPATA13 SUMO2	3 interacting genes: CDC42 GALK1 KHDRBS1
Entrez ID		2584	221178
HPRD ID		05057	15427
Ensembl ID		ENSG00000108479	ENSG00000182957
Uniprot IDs		P51570 V9HWE7	A0A024RDM6 B4DMC2 E9PFR9 Q96N96
PDB IDs		1WUU 1YH7 6GR2 6Q3W 6Q3X 6Q8Z 6Q90 6Q91 6QJE 6ZGV 6ZGW 6ZGX 6ZGY 6ZGZ
Enriched GO Terms of Interacting Partners?
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