PPP3R1 and CABP1

Number of citations of the paper that reports this interaction (PubMedID 11108966)
18

Data Source:
BioGRID (pull down)

		PPP3R1	CABP1
Description		protein phosphatase 3 regulatory subunit B, alpha	calcium binding protein 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Calcineurin Complex Sarcolemma Schaffer Collateral - CA1 Synapse Parallel Fiber To Purkinje Cell Synapse Postsynapse Glutamatergic Synapse	Golgi Membrane Extracellular Space Cytoskeleton Plasma Membrane Cell Cortex Postsynaptic Density Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium-dependent Protein Serine/threonine Phosphatase Activity Calcium Ion Binding Protein Binding Calmodulin Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity Cyclosporin A Binding Phosphatase Binding Protein Domain Specific Binding	Enzyme Inhibitor Activity Calcium Ion Binding Protein Binding Nuclear Localization Sequence Binding Calcium-dependent Protein Binding
	Biological Process	Branching Involved In Blood Vessel Morphogenesis Epithelial To Mesenchymal Transition Protein Dephosphorylation Protein Import Into Nucleus Heart Development Myelination In Peripheral Nervous System Calcineurin-NFAT Signaling Cascade Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Catalytic Activity Lung Epithelial Cell Differentiation Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Postsynaptic Modulation Of Chemical Synaptic Transmission	Visual Perception Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Catalytic Activity Response To Stimulus
Pathways		Activation of BAD and translocation to mitochondria DARPP-32 events Calcineurin activates NFAT Calcineurin activates NFAT FCERI mediated Ca+2 mobilization Ca2+ pathway CLEC7A (Dectin-1) induces NFAT activation	Sensory processing of sound by inner hair cells of the cochlea
Drugs		Myristic acid Voclosporin
Diseases
GWAS		General cognitive ability ( 29844566) Height ( 25282103) Hip index ( 34021172) Intelligence (MTAG) ( 29326435) Schizophrenia ( 30285260) Urinary potassium excretion ( 31409800)	C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Chronotype ( 30696823) Serum metabolite levels ( 33031748) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systemic lupus erythematosus ( 33536424)
Interacting Genes		11 interacting genes: CABP1 CABP2 CABP5 CHRNA6 MAP3K5 NAP1L2 NFATC1 NFATC2 PPP3CA PPP3CC WDPCP	11 interacting genes: CACNA1A CACNA1C CSNK2A2 FOS GRK5 ITPR1 ITPR3 MPHOSPH9 NMT1 PPP3R1 SLC9A3R1
Entrez ID		5534	9478
HPRD ID		03195	12025
Ensembl ID		ENSG00000221823	ENSG00000157782
Uniprot IDs		P63098	Q9NZU7
PDB IDs		1AUI 1M63 1MF8 2P6B 3LL8 4F0Z 4OR9 4ORA 4ORC 5SVE 6NUC 6NUF 6NUU	2K7B 2K7C 2K7D 2LAN 2LAP 3OX5 3OX6
Enriched GO Terms of Interacting Partners?
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