TMEM40 and NUP210

		TMEM40	NUP210
Description		transmembrane protein 40	nucleoporin 210
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function		Protein Binding
	Biological Process		Protein Transport MRNA Transport Protein-containing Complex Assembly
Pathways			ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Left ventricular ejection fraction ( 32605384) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		1 interacting genes: NUP210	8 interacting genes: ADGRG2 CDK1 EXOSC5 HDAC11 MTDH TMEM40 TRIP6 TSEN2
Entrez ID		55287	23225
HPRD ID		08559	06368
Ensembl ID		ENSG00000088726	ENSG00000132182
Uniprot IDs		B4DXI0 Q8WWA1	Q8TEM1
PDB IDs
Enriched GO Terms of Interacting Partners?
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