PTPA and PPP2R3A

Number of citations of the paper that reports this interaction (PubMedID 18397887)
17

Data Source:
BioGRID (pull down)

		PTPA	PPP2R3A
Description		protein phosphatase 2 phosphatase activator	protein phosphatase 2 regulatory subunit B''alpha
Image
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Nucleoplasm Cytoplasm Calcium Channel Complex Extracellular Exosome	Protein Phosphatase Type 2A Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Protein Binding ATP Binding Protein Tyrosine Phosphatase Activator Activity ATP Hydrolysis Activity Protein Phosphatase Regulator Activity Protein Homodimerization Activity Protein Phosphatase 2A Binding	Calcium Ion Binding Protein Binding Protein Phosphatase Regulator Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Mitotic Spindle Organization Negative Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Apoptotic Process Regulation Of Phosphoprotein Phosphatase Activity	Protein Dephosphorylation Regulation Of Catalytic Activity Somite Development
Pathways
Drugs
Diseases
GWAS			Anticoagulant levels ( 22216198) Atrial fibrillation ( 30061737) Autism spectrum disorder or schizophrenia ( 28540026) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Feeling nervous ( 29500382) Feeling worry ( 29500382) Fibrinogen levels ( 28107422 26561523) General factor of neuroticism ( 30867560) High density lipoprotein cholesterol levels ( 31928498) Intraocular pressure ( 29617998) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Myocardial infarction ( 33532862) Neurofibrillary tangles ( 31497858) Neutrophil percentage of white cells ( 32888494) Schizophrenia ( 25056061 29483656) Small cell lung carcinoma ( 28604730) Systolic blood pressure ( 31928498) Triglyceride levels ( 31928498) Waist circumference ( 31928498) Waist circumference adjusted for body mass index ( 34021172 25673412) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		29 interacting genes: AKT1 AMOT APP AURKB CCDC125 CCNE1 CCNG1 CCNG2 CSNK2A1 CYLD DTD1 EIF4EBP1 F3 FOXO3 GRIN3A H2AX HDAC4 KISS1R MAPT MID1 NIF3L1 PPP2R1A PPP2R3A PRKCB RACGAP1 SPG21 SRC SULT4A1 TSC1	9 interacting genes: AKAP9 ATR ATXN7L2 CDC6 HMGB1 NPHP3 PPP5C PTPA RBL1
Entrez ID		5524	5523
HPRD ID		02858	09225
Ensembl ID		ENSG00000119383	ENSG00000073711
Uniprot IDs		B4DZF8 F6WIT2 Q15257	Q06190
PDB IDs		2G62 2HV6 2HV7 2IXM 4LAC 4NY3	4I5J 4I5K
Enriched GO Terms of Interacting Partners?
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