SMU1 and LSM8

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid)

		SMU1	LSM8
Description		SMU1 DNA replication regulator and spliceosomal factor	LSM8 homolog, U6 small nuclear RNA associated
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GO Annotations	Cellular Component	Nucleus Cytoplasm Nuclear Speck U2-type Precatalytic Spliceosome Precatalytic Spliceosome	Nucleus Nucleoplasm U6 SnRNP U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Lsm2-8 Complex
	Molecular Function	Protein Binding	RNA Binding Protein Binding U6 SnRNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Splicing	MRNA Splicing, Via Spliceosome RNA Metabolic Process
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Glaucoma (primary open-angle) ( 33627673 29891935) Intraocular pressure ( 29617998) Plasma anti-thyroid peroxidase levels ( 29678681) Positive urgency ( 30718321) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Smoking initiation ( 33082346) Smoking status (current vs never) ( 33082346) Triglyceride levels ( 30108155)
Interacting Genes		11 interacting genes: CD2BP2 CERT1 H2BC21 LSM4 LSM8 MRFAP1 MRFAP1L1 MSS51 RASSF10 TLX3 YBX1	49 interacting genes: ARNT BCKDK COL23A1 DBF4 DCP1A DCP1B DPAGT1 ECHDC2 EFTUD2 EXOSC10 EXOSC6 FERMT3 GMPPA GTF2I HSPA9 IFNLR1 IGHMBP2 ISOC2 ITSN2 KCTD3 LSM2 LSM3 LSM5 LSM6 LSM7 MAPK8IP2 MGA MINDY1 MPRIP MRPL48 MTHFR NAGK NME4 PDCD2 PGD PHF11 RBM5 RPL24 RSC1A1 RSL24D1 SEPTIN10 SEPTIN5 SMU1 SNRNP200 SNRPB SNRPD1 TALDO1 THUMPD3 UPF1
Entrez ID		55234	51691
HPRD ID		11588	06288
Ensembl ID		ENSG00000122692	ENSG00000128534
Uniprot IDs		A0MNN4 Q2TAY7	A4D0W0 O95777
PDB IDs		5O9Z 6AHD 6Q8F 6Q8I 6Q8J	3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9 7ABG
Enriched GO Terms of Interacting Partners?
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