SBNO1 and DIABLO

		SBNO1	DIABLO
Description		strawberry notch homolog 1	diablo IAP-binding mitochondrial protein
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus	Mitochondrion Mitochondrial Intermembrane Space Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex
	Molecular Function	Molecular_function Chromatin DNA Binding Histone Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Biological_process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Positive Regulation Of Apoptotic Process Neuron Apoptotic Process Intrinsic Apoptotic Signaling Pathway
Pathways			Release of apoptotic factors from the mitochondria SMAC (DIABLO) binds to IAPs SMAC (DIABLO) binds to IAPs SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC, XIAP-regulated apoptotic response Regulation of the apoptosome activity
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Allergy ( 27182965) Autism spectrum disorder or schizophrenia ( 28540026) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 27618447) Educational attainment ( 25201988) HDL cholesterol ( 24097068 30275531 20686565) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Head circumference (infant) ( 22504419) Height ( 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Knee osteoarthritis ( 30374069) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lymphocyte counts ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252) Plateletcrit ( 32888494) Schizophrenia ( 25056061 29483656 23974872) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Body shape index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: ANAPC5 ARL6IP4 DIABLO GSK3A TRIAP1 ZCCHC8	43 interacting genes: AGTRAP APOC2 APOC4 AREL1 ARL6IP1 ARNT BEX3 BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 CASP9 CMTM4 DERL2 DGAT2L6 DHRS1 E2F1 EEF1A1 FADS6 FKBP7 HSD17B13 HTRA2 LTBR MAML2 MICOS13 MPC2 NR4A1 RHBDD2 RMDN2 SBNO1 SEC22A SFT2D1 SLC17A9 SLC25A47 SLC66A2 STMN4 SYP TIMMDC1 UBE2K UFM1 XIAP ZNF746
Entrez ID		55206	56616
HPRD ID		11533	05560
Ensembl ID		ENSG00000139697	ENSG00000184047
Uniprot IDs		A3KN83	A0A024RBT2 A0A0S2Z5P6 A0A0S2Z5U7 K7X1S0 Q502X2 Q9NR28
PDB IDs			1FEW 1G3F 1G73 1OXQ 1TW6 1XB0 1XB1 3D9U 3UIH 3UIJ 4TX5 6JX6
Enriched GO Terms of Interacting Partners?
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