ARHGEF10L and ANXA9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		ARHGEF10L	ANXA9
Description		Rho guanine nucleotide exchange factor 10 like	annexin A9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Cell Surface Vesicle Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity	Phosphatidylserine Binding Protease Binding Calcium Channel Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding Phosphatidylinositol-4,5-bisphosphate Binding Acetylcholine Receptor Activity Phospholipase A2 Inhibitor Activity Virion Binding
	Biological Process	Actin Cytoskeleton Organization SREBP Signaling Pathway Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Stress Fiber Assembly	Synaptic Transmission, Cholinergic Negative Regulation Of Catalytic Activity Calcium Ion Transmembrane Transport Cell-cell Adhesion
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle
Drugs
Diseases
GWAS		Basal cell carcinoma ( 18849993) Initial pursuit acceleration in psychotic disorders ( 29064472) Insomnia ( 27992416) Major depressive disorder x sex interaction ( 34099189) Obesity-related traits ( 23251661) Response to hepatitis C treatment ( 22095909)	Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 26426971) Chronic kidney disease ( 20383146) Estimated glomerular filtration rate ( 30604766) Facial attractiveness (female raters) ( 30946739) Glomerular filtration rate (creatinine) ( 28452372) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol ( 24097068) LDL cholesterol levels ( 28334899) Mean spheric corpuscular volume ( 32888494) Melanoma ( 21926416 21983785) Morning person ( 30696823) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Rhegmatogenous retinal detachment ( 23585552)
Interacting Genes		4 interacting genes: ANXA9 DRAP1 NR4A1 SCN2A	3 interacting genes: APP ARHGEF10L NDUFA4L2
Entrez ID		55160	8416
HPRD ID		07679	11938
Ensembl ID		ENSG00000074964	ENSG00000143412
Uniprot IDs		B4DTL3 Q5VXI4 Q9HCE6	O76027
PDB IDs
Enriched GO Terms of Interacting Partners?
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