ANO10 and SMARCA2

Number of citations of the paper that reports this interaction (PubMedID 21653829)
98

Data Source:
BioGRID (two hybrid)

		ANO10	SMARCA2
Description		anoctamin 10	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Chromatin Nucleus Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle Intermediate Filament Cytoskeleton NpBAF Complex NBAF Complex
	Molecular Function	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity	Transcription Cis-regulatory Region Binding DNA Binding Chromatin Binding Transcription Coactivator Activity Helicase Activity Protein Binding ATP Binding ATP-dependent Activity, Acting On DNA Hydrolase Activity Histone Binding ATP-dependent Chromatin Remodeler Activity
	Biological Process	Cation Transport Chloride Transport Ion Transmembrane Transport Transmembrane Transport Cation Transmembrane Transport	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Spermatid Development Nervous System Development Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Stimuli-sensing channels	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Body shape index ( 34021172) Gastroesophageal reflux disease ( 31527586) Obesity-related traits ( 23251661) Primary central nervous system lymphoma ( 31102405) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Arterial stiffness (brachial-femoral pulse wave velocity) ( 32790701) Asthma (childhood onset) ( 27611488) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Brain morphology (MOSTest) ( 32665545) Lead levels ( 26025379) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Monobrow ( 27182965) Neuritic plaque ( 31497858) Nose size ( 27182965) Parkinson's disease ( 26227905) Superior frontal gyrus grey matter volume ( 25335168) Systolic blood pressure ( 26969751) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955)
Interacting Genes		3 interacting genes: HTR4 SMARCA2 TRANK1	54 interacting genes: ACTL6A ACTL6B ACTN2 ANO10 APC2 AR ARID1B BEND7 BRCA1 CCDC136 CEBPA CEP72 CNTROB CXXC1 DAB2IP DNM2 ESR1 GAPDH GCC1 GFAP H3C1 HSPB1 ITPRID2 KHDRBS1 LAMC1 MDM2 MDM4 MECP2 MPRIP MYB MYC MYO5B NECAB2 NR0B2 NR3C1 NR4A2 NUP62 PHB PICK1 PITX1 PPFIA2 PPP1R12C PRMT5 PRPF6 RAP1A SDCBP SIN3B SMARCC2 SPAG5 SS18 SUPT4H1 TACC2 TNFAIP1 ZNF821
Entrez ID		55129	6595
HPRD ID		07667	02483
Ensembl ID		ENSG00000160746	ENSG00000080503
Uniprot IDs		A0A024R2S0 Q9NW15	B1ALF6 B4DNT1 B4DSC8 F6T8Q0 F6VDE0 P51531 Q56A76 Q8N9Q1
PDB IDs		5OC9 6R65 6R7X 6R7Y 6R7Z	2DAT 4QY4 5DKC 5DKH 6EG2 6EG3 6HAX 6HAY 6HAZ
Enriched GO Terms of Interacting Partners?
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