CEP192 and SPIRE1

		CEP192	SPIRE1
Description		centrosomal protein 192	spire type actin nucleation factor 1
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GO Annotations	Cellular Component	Pericentriolar Material Cytoplasm Centrosome Centriole Cytosol	Nucleoplasm Cytosol Cytoskeleton Cell Cortex Cytoplasmic Vesicle Membrane Integral Component Of Mitochondrial Outer Membrane Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Phosphatase Binding	Actin Binding Protein Binding
	Biological Process	Centriole Replication Response To Bacterium Protein Localization To Centrosome Centrosome-templated Microtubule Nucleation Mitotic Spindle Assembly	Protein Transport Vesicle-mediated Transport Actin Cytoskeleton Organization Actin Filament Polymerization Cleavage Furrow Formation Polar Body Extrusion After Meiotic Divisions Actin Nucleation Intracellular Transport Golgi Vesicle Transport Establishment Of Meiotic Spindle Localization Actin Filament Network Formation Formin-nucleated Actin Cable Assembly Positive Regulation Of Mitochondrial Fission Positive Regulation Of Double-strand Break Repair
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
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Diseases
GWAS		Appendicular lean mass ( 33097823) General cognitive ability ( 29844566)	Carotid plaque burden ( 28282560) Hematocrit ( 32888494) Hemoglobin ( 32888494) Immune response to smallpox vaccine (IL-6) ( 22542470) Red blood cell count ( 32888494)
Interacting Genes		5 interacting genes: CTAGE1 LINC00839 SHBG SPIRE1 UBC	4 interacting genes: BBS4 CEP192 ETS1 PLEKHA5
Entrez ID		55125	56907
HPRD ID		10855	11600
Ensembl ID		ENSG00000101639	ENSG00000134278
Uniprot IDs		Q8TEP8 Q9HCK3	Q08AE8
PDB IDs		4N7Z 6FVI 6W3J	2YLE 2YLF 3R7G 3RBW
Enriched GO Terms of Interacting Partners?
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