NRDE2 and ITGB3BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		NRDE2	ITGB3BP
Description		NRDE-2, necessary for RNA interference, domain containing	integrin subunit beta 3 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck	Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Molecular_function Protein Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Mitotic Cell Cycle MRNA Processing Cellular Response To DNA Damage Stimulus RNA Splicing RNA Interference Heterochromatin Assembly By Small RNA Positive Regulation Of RNA Export From Nucleus Cell Division Negative Regulation Of RNA Catabolic Process	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Cell Division
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Lifespan ( 25918517) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Mean spheric corpuscular volume ( 32888494)
Interacting Genes		11 interacting genes: ARFIP2 CCDC183 HAUS8 ITGB3BP LHX3 MED29 MESD RCOR3 SPG21 UQCC2 VPS28	43 interacting genes: ACTN2 ANKRD11 APP ARFIP2 C14orf119 CCNA2 CERT1 DDX24 EFHC1 ESR1 GATAD2A GTPBP3 HSF2BP ITGB3 ITGB5 KDM1A KIAA0930 KIFC3 LRRK2 MAPK6 MAPK9 MEIS2 MEOX2 MSGN1 MTA1 NFKB1 NRDE2 NTAQ1 PBX3 PIH1D2 PIK3R3 RECQL5 RELA RXRA RXRG SNAPC5 SUOX SVIL THRA TRIML2 UBR7 USHBP1 USP20
Entrez ID		55051	23421
HPRD ID		12625	09267
Ensembl ID		ENSG00000119720	ENSG00000142856
Uniprot IDs		Q9H7Z3	D3DQ59 Q13352
PDB IDs		6IEH
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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