ITGB3BP and GTPBP3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ITGB3BP	GTPBP3
Description		integrin subunit beta 3 binding protein	GTP binding protein 3, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding Protein C-terminus Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Cell Division	TRNA Wobble Uridine Modification TRNA Methylation
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	tRNA modification in the mitochondrion
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494)	Mitochondrial DNA copy number ( 30704525)
Interacting Genes		43 interacting genes: ACTN2 ANKRD11 APP ARFIP2 C14orf119 CCNA2 CERT1 DDX24 EFHC1 ESR1 GATAD2A GTPBP3 HSF2BP ITGB3 ITGB5 KDM1A KIAA0930 KIFC3 LRRK2 MAPK6 MAPK9 MEIS2 MEOX2 MSGN1 MTA1 NFKB1 NRDE2 NTAQ1 PBX3 PIH1D2 PIK3R3 RECQL5 RELA RXRA RXRG SNAPC5 SUOX SVIL THRA TRIML2 UBR7 USHBP1 USP20	29 interacting genes: BEND7 CAPN3 CCDC32 CIC COPS5 DCAF8 DPPA4 GNE INCA1 ITGB3BP MBD3L1 MEOX2 MESD OGT PARP11 PFKL POLDIP3 PPP1R18 PRPF3 PTAFR RALY RIBC2 SERTAD3 SINHCAF TBC1D3B TBC1D3G ZFP90 ZNF69 ZNF774
Entrez ID		23421	84705
HPRD ID		09267	12255
Ensembl ID		ENSG00000142856	ENSG00000130299
Uniprot IDs		D3DQ59 Q13352	B7Z563 Q969Y2
PDB IDs
Enriched GO Terms of Interacting Partners?
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