LAMTOR1 and CCDC90B

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LAMTOR1	CCDC90B
Description		late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	coiled-coil domain containing 90B
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GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Plasma Membrane Late Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Membrane Raft Extracellular Exosome Ragulator Complex Ficolin-1-rich Granule Membrane	Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding GTPase Binding Molecular Adaptor Activity	Protein Binding
	Biological Process	Regulation Of Cell Growth Regulation Of Receptor Recycling Endosome Organization Lysosome Organization Regulation Of Cholesterol Esterification Regulation Of Cholesterol Efflux Endosomal Transport Positive Regulation Of TOR Signaling Lysosome Localization Cellular Protein Localization Cholesterol Homeostasis Positive Regulation Of MAPK Cascade Regulation Of Catalytic Activity Regulation Of Cholesterol Import Cellular Response To Amino Acid Stimulus
Pathways		Macroautophagy MTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Neutrophil degranulation Regulation of PTEN gene transcription CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOQ GTPase cycle RHOH GTPase cycle RHOG GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle Amino acids regulate mTORC1
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: ABCF3 CAPN1 CCDC90B CTAG1A CTAG1B EEF1A1 TRIM14	31 interacting genes: AGR2 ANXA7 ARL15 BTBD2 CDKN2B CDKN2C DLEU1 DNM2 EIF2S2 FXYD6 GORASP2 KDM1A LAMTOR1 MOB2 NACA NIPSNAP3A PAFAH1B3 PCDHA4 PIN1 PNP PRDX5 PSMD11 RGL2 RNF10 SAT1 SDHAF2 SERPINB9 SMN1 TAC3 TK1 TSC22D1
Entrez ID		55004	60492
HPRD ID		07933	14378
Ensembl ID		ENSG00000149357	ENSG00000137500
Uniprot IDs		Q6IAA8	Q9GZT6
PDB IDs		5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG 6WJ2 6WJ3	6H9M
Enriched GO Terms of Interacting Partners?
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